Numerical Simulation and Experimental Studies of a Ribbon Coil for Trans Spinal Magnetic Stimulation (TSMS) in Rats.

Numerical Simulation and Experimental Studies of a Ribbon Coil for Trans Spinal Magnetic Stimulation (TSMS) in Rats.
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用于大鼠经脊柱磁刺激 (TSMS) 的带状线圈的数值模拟和实验研究。

DOI:
10.1109/embc40787.2023.10340213
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发表时间:
2023
期刊:
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
影响因子:
--
通讯作者:
Bonmassar,Giorgio
Bonmassar,Giorgio
中科院分区:
--
文献类型:
--
作者:
Colella,Micol;Cid,LidiaGomez;Liberti,Micaela;Apollonio,Francesca;Yu,Xin;Ay,Ilknur;Bonmassar,Giorgio

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我们提出了一种非侵入性的经脊髓磁刺激(TSMS)线圈,允许局部刺激。该设备基于新的8字形带状设计,确保低R0和低发热。采用神经元耦合有限元方法对两种线圈进行了设计和研究,并在大鼠身上进行了疗效测试。数值模拟证实了当线圈以2.8kA驱动时,观察到的动作电位的产生。临床相关性:慢性神经病理性背痛和腿痛是美国脊髓刺激的主要适应症之一。慢性下腰痛是患者求医的最常见原因之一,2013年,美国的医疗费用达到876亿美元。与并发症发生率高的手术相比,患者更倾向于低风险、非侵入性的手术,如TSMS。
We propose a non-invasive Trans Spinal Magnetic Stimulation (TSMS) coil allowing for focal stimulation. The device is based on a new figure-8 ribbon design, ensuring low R0, and low heating. The two coils were designed and studied using the finite element method (FEM) coupled with NEURON and tested for efficacy on rats. The numerical simulations confirmed the generation of the observed action potentials when the coil was driven with 2.8kA.Clinical Relevance— Chronic neuropathic back and leg pain is one of the main indications for spinal cord stimulation in the United States. Chronic low back pain is one of the most common reasons patients seek medical care, and in 2013 resulted in 87.6 billion dollars in healthcare costs in the USA. Patients would most likely prefer a low-risk, non-invasive procedure, such as TSMS, to surgery with a significant rate of complications.
DOI: --
发表时间: 1979
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