Sample design and cohort selection in the Hispanic Community Health Study/Study of Latinos.
Sample design and cohort selection in the Hispanic Community Health Study/Study of Latinos.
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DOI：
10.1016/j.annepidem.2010.05.006
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发表时间：
2010-08
影响因子：
5.6
通讯作者：
Elder, John P.
中科院分区：
文献类型：
--
作者：
Lavange, Lisa M.;Kalsbeek, William D.;Sorlie, Paul D.;Aviles-Santa, Larissa M.;Kaplan, Robert C.;Barnhart, Janice;Liu, Kiang;Giachello, Aida;Lee, David J.;Ryan, John;Criqui, Michael H.;Elder, John P.
西班牙裔社区健康研究（HCHS）/拉丁裔研究（SOL）是一项针对美国西班牙裔/拉丁裔成年人的多中心、基于社区的队列研究。需要一个多样化的参与者样本，既要能代表目标人群，又要有可能在整个随访过程中保持参与。本文描述了样本设计的选择、其基本原理以及设计决策的优点和挑战。
研究设计要求招募并随访一个由16000名18 - 74岁的西班牙裔/拉丁裔组成的队列，其中62.5%（10000人）年龄在44岁以上，并且有足够的亚组样本量以支持按西班牙裔/拉丁裔背景进行推断。参与者是从布朗克斯、芝加哥、迈阿密和圣地亚哥四个现场中心周围的社区招募的。采用两阶段区域概率抽样选取家庭，在每个阶段都进行分层和过度抽样，以提供一个广泛多样的样本，提高现场操作的效率，并确保获得目标年龄分布。
在这种传统的多站点队列研究设计中嵌入概率抽样能够满足相互竞争的研究目标。然而，概率抽样的使用需要针对样本选择和招募方面的一些独特挑战制定解决方案，如下文所述。
The Hispanic Community Health Study (HCHS)/Study of Latinos (SOL) is a multi-center, community based cohort study of Hispanic/Latino adults in the United States. A diverse participant sample is required that is both representative of the target population and likely to remain engaged throughout follow-up. The choice of sample design, its rationale, and benefits and challenges of design decisions are described in this paper. The study design calls for recruitment and follow-up of a cohort of 16,000 Hispanics/Latinos aged 18-74 years, with 62.5% (10,000) over 44 years of age and adequate subgroup sample sizes to support inference by Hispanic/Latino background. Participants are recruited in community areas surrounding four field centers in the Bronx, Chicago, Miami, and San Diego. A two-stage area probability sample of households is selected with stratification and over-sampling incorporated at each stage to provide a broadly diverse sample, offer efficiencies in field operations, and ensure that the target age distribution is obtained. Embedding probability sampling within this traditional, multi-site cohort study design enables competing research objectives to be met. However, the use of probability sampling requires developing solutions to some unique challenges in both sample selection and recruitment, as described here.
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影响因子：
5.6
作者：
Sorlie, Paul D.;Aviles-Santa, Larissa M.;Wassertheil-Smoller, Sylvia;Kaplan, Robert C.;Daviglus, Martha L.;Giachello, Aida L.;Schneiderman, Neil;Raij, Leopoldo;Talavera, Gregory;Allison, Matthew;Lavange, Lisa;Chambless, Lloyd E.;Heiss, Gerardo
通讯作者：
Heiss, Gerardo
影响因子：
2
作者：
KRUSKAL, W;MOSTELLER, F
通讯作者：
MOSTELLER, F
影响因子：
12.7
作者：
WINKLEBY, MA;JATULIS, DE;FORTMANN, SP
通讯作者：
FORTMANN, SP
DOI：
10.1111/j.1467-985x.2007.00526.x
发表时间：
2008-01-01
影响因子：
2
作者：
Michael, Robert T.;O'Muircheartaigh, Colm A.
通讯作者：
O'Muircheartaigh, Colm A.
DOI：
10.1198/016214504000000467
发表时间：
2004-06-01
影响因子：
3.7
作者：
Little, RJ
通讯作者：
Little, RJ