Progesterone and the luteal phase: a requisite to reproduction.
Progesterone and the luteal phase: a requisite to reproduction.
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DOI:
10.1016/j.ogc.2014.10.003
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发表时间:
2015-03
影响因子:
3.2
通讯作者:
Young SL
中科院分区:
文献类型:
--
作者:
Mesen TB;Young SL
The normal menstrual cycle can be divided into two phases: follicular and luteal, which are separated by ovulation and bookended by the first day of menstrual bleeding. The follicular phase is dominated by the development of the preovulatory follicle, resulting in estrogenstimulated endometrial proliferation, whereas the corpus luteum (CL) of its namesake luteal phase produces progesterone, which inhibits endometrial proliferation and determines endometrial receptivity. Without both phases working in series, natural reproduction is not possible. This article focuses on the normal physiology of the luteal phase, investigates the controversy surrounding luteal phase defect, and describes the role of luteal phase support in assisted reproductive technology (ART).
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