Efficacy of chuanxiong ding tong herbal formula granule in the treatment and prophylactic of migraine patients: a randomized, double-blind, multicenter, placebo-controlled trial.
Efficacy of chuanxiong ding tong herbal formula granule in the treatment and prophylactic of migraine patients: a randomized, double-blind, multicenter, placebo-controlled trial.
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DOI：
10.1155/2012/967968
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Lin D
中科院分区：
文献类型：
--
作者：
Fu C;Yu L;Zou Y;Cao K;Zhao J;Gong H;Zhang S;Lin A;Dong M;Yang W;Li T;He L;Su F;Wu R;Lin D
Objective. To evaluate the efficacy of traditional Chinese herbal ChuanXiong Ding Tong herbal formula granule (CXDT-HFG) for migraine patients with “the Syndrome of Liver Wind and Blood Stasis.” Methods. 150 migraine patients were recruited and assigned randomly in a double-blind, placebo-controlled study to receive CXDT-HFG (n = 99) plus necessary analgesics, or placebo (n = 51) plus necessary analgesics for 16 weeks (12 weeks' intervention and 4 weeks' follow up). Outcome measures included migraine days, frequency of migraine attacks, analgesics consumption for acute treatment, and the proportion of responders as well as the visual analogue scale (VAS) scores and intensity for pain. Results. Compared with the placebo group, the CXDT-HFG group showed significant reduction in migraine days and attacks frequency at week 12 and follow-up period (P < 0.05) as well as in the reduction of VAS scores at follow-up period.There was significant difference in the proportion of responders between the two groups at follow-up period (P = 0.014). However there were no significant differences between the two groups in analgesics consumption (P > 0.05). Conclusion. CXDT-HFG was more effective than placebo in decreasing days of migraine attacks, frequency, VAS scores, and relieving pain intensity for migraine patients.
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影响因子：
--
作者：
Day, SJ;Altman, DG
通讯作者：
Altman, DG
影响因子：
9.9
作者：
Silberstein, SD
通讯作者：
Silberstein, SD
DOI：
10.1155/2012/984295
发表时间：
2012
期刊：
Evidence-based complementary and alternative medicine : eCAM
影响因子：
--
作者：
Chang CL;Lin CS;Lai GH
通讯作者：
Lai GH
影响因子：
2.6
作者：
Voigt, Karen;Liebnitzky, Jan;Bergmann, Antje
通讯作者：
Bergmann, Antje
影响因子：
4.9
作者：
Silberstein, SD
通讯作者：
Silberstein, SD