The Pre-exposure Prophylaxis (PrEP) Care Cascade in People Who Inject Drugs: A Systematic Review.

The Pre-exposure Prophylaxis (PrEP) Care Cascade in People Who Inject Drugs: A Systematic Review.
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注射药物的人的暴露前预防(PREP)护理级联:系统评价。

DOI:
10.1007/s10461-020-02988-x
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发表时间:
2021-05
期刊:
影响因子:
4.4
通讯作者:
Shrestha R
Shrestha R
中科院分区:
医学2区
文献类型:
--
作者:
Mistler CB;Copenhaver MM;Shrestha R

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注射吸毒是传播艾滋病毒的一个关键危险因素。预防策略,例如使用暴露前预防 (PrEP),可有效降低注射吸毒者 (PWID) 传播艾滋病毒的风险。根据 PRISMA 指南,进行了文献检索以确定吸毒者 PrEP 护理级联的现状。本次系统评价评估了 23 篇文章。研究发现,PrEP 护理级联各个阶段的参与度均有所下降。使用 PrEP 的意识和意愿较高,但 PrEP 的使用率相对较低(0-3%)。目前缺乏关于提高吸毒者各级护理级联中 PrEP 参与度的干预措施的研究。已发表的干预措施的意义提供了对减少吸毒者艾滋病毒发病率有效策略的实践和公共政策的见解。我们的研究结果表明,需要付出更多努力来识别和筛查吸毒者的 PrEP 资格,并将其与适当的 PrEP 护理联系起来并维持。
Injection drug use is a key risk factor for the transmission of HIV. Prevention strategies, such as the use of pre-exposure prophylaxis (PrEP), are effective at reducing the risk of HIV transmission in people who inject drugs (PWID). Following PRISMA guidelines, a literature search was conducted to identify the current state of the PrEP care cascade in PWID. Twenty-three articles were evaluated in this systematic review. A decline in engagement throughout the stages of the PrEP care cascade was found. High awareness and willingness to use PrEP was found, yet PrEP uptake was relatively low (0–3%). There is a lack of research on interventions to increase engagement of PrEP across all levels of the care cascade in PWID. Implications from the interventions that have been published provide insight into practice and public policy on efficacious strategies to reduce HIV incidence in PWID. Our findings suggest that more efforts are needed to identify and screen PWID for PrEP eligibility and to link and maintain them with appropriate PrEP care.
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