Unit activity in the cerebellar nuclei related to arm reaching movements
Unit activity in the cerebellar nuclei related to arm reaching movements
复制标题
小脑核的单位活动与手臂伸展运动相关
DOI：
10.1016/0006-8993(88)91509-0
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发表时间：
1988
期刊：
影响因子：
2.9
通讯作者：
W. A. Mackay
中科院分区：
文献类型：
--
作者：
W. A. Mackay
研究了两只短尾猴疲劳核、间位核和齿状核中的单个单位与右臂视觉引导到达任务的关系。在记录的638个细胞中，149个显示出与任务相关的活动变化，其中24个位于对侧顶叶和间位。与REACH相关的放电模式可分为两大类，强直性和相位性。紧张性反应在整个河段都保持不变，与运动学参数没有明显关系。大多数与任务相关的活动发生在手臂朝目标按钮向上抬起的过程中，随着手臂向休息板下降，与任务相关的活动会减少。相位反应细胞在手臂轨迹中的特定点发出猝发(或抑制放电)，最常见的是在抬起阶段。当肩部屈曲扭矩被瞬间反转以减速手臂时，许多人的排泄量急剧下降。对于任何一种类型，限制性方向特异性在任何核团中都是罕见的，并且与记录的EMG的相关性很弱。顶核和齿状核都观察到了对目标按钮照射的视觉反应，但不一定与给予最佳运动相关反应的按钮相对应。与任务相关的活动变化最早开始于顶核，最晚开始于间位核。数据表明，小脑输出以一种相当普遍的方式促进运动中枢，但在精确确定的时间。
Single units in the fatigial, interpositus and dentate nuclei of two stump-tail macaque monkeys were studied in relation to a right arm, visually guided reaching task. Of 638 recorded cells, 149 showed activity changes correlated to the task, including 24 in the contralateral fastigial and interpositus. Reach-related discharged patterns fell into two broad categories, tonic and phasic. Tonic responses were maintained throughout the reach with no observable relation to kinematic parameters. Most of the task-related activity occured during the upward lift of the arm toward the target button, with a drop-offas the arm was lowered toward the rest plate. Phasic response cells fired burst (or suppressed discharge) at specific points in the arm trajectory, most commonly during the lift phase. Many had a sharp drop in discharge when the shoulder flexion torque was transiently reversed to decelerate the arm. For either type, restricted directional specificity was rerely seen in any nucleus, and correlations with recorded EMGs were weak. Visual responses to target button illumination were observed in both the fastigial and dentate nuclei, but did not necessarily correspond with the button giving the best movement-related response. Task-related activity changes started earliest in the fastigial nuclei and latest in the interpositus nuclei. The data suggested that cerebellar output facilitates motor centers in a rather general manner, but at precisely determined times.
受训猕猴红核放电与运动参数之间的关系。
DOI：
10.1113/jphysiol.1985.sp015566
发表时间：
1985
期刊：
The Journal of physiology
影响因子：
--
作者：
Gibson,AR;Houk,JC;Kohlerman,NJ
通讯作者：
Kohlerman,NJ
影响因子：
2.5
作者：
Schieber,MH;ThachJr,WT
通讯作者：
ThachJr,WT