Urinary stone differentiation in patients with large body size using dual-energy dual-source computed tomography.

Urinary stone differentiation in patients with large body size using dual-energy dual-source computed tomography.
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DOI:
10.1007/s00330-012-2727-4
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发表时间:
2013-05
期刊:
影响因子:
5.9
通讯作者:
McCollough CH
McCollough CH
中科院分区:
医学2区
文献类型:
--
作者:
Qu M;Jaramillo-Alvarez G;Ramirez-Giraldo JC;Liu Y;Duan X;Wang J;Vrtiska TJ;Krambeck AE;Lieske J;McCollough CH

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To evaluate the ability of 100/Sn140 kV (Sn, tin filter) dual-energy CT to differentiate urinary stone types in a patient cohort with a wide range of body sizes. 80 human urinary stones were categorised into four groups (uric acid; cystine; struvite, oxalate and brushite together; and apatite) and imaged in 30–50-cm wide water tanks using clinical 100/Sn140 kV protocols. The CT number ratio (CTR) between the low- and high-energy images was calculated. Thresholds for differentiating between stone groups were determined using ROC analysis. Additionally, 86 stones from 66 patients were characterised using the size-adaptive CTR thresholds determined in the phantom study. In phantoms, the area under the ROC curve for differentiating between stone groups ranged from 0.71 to 1.00, depending on phantom size. In patients, body width ranged from 28.5 to 50.0 cm, and 79.1% of stones were correctly characterised. Sensitivity and specificity for correctly identifying the stone category were 100% and 100% (group 1), 100% and 95.3% (group 2), 85.7% and 60.9% (group 3), and 52.6% and 92.5% (group 4). Dual-energy CT can provide in vivo urinary stone characterisation for patients over a wide range of body sizes.
DOI: 10.2214/ajr.10.5041
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期刊: AJR. American journal of roentgenology
影响因子: --
作者:
Qu M;Ramirez-Giraldo JC;Leng S;Williams JC;Vrtiska TJ;Lieske JC;McCollough CH
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