Endplate Deficits and Posterior Wall Injury Are Predictive of Prolonged Back Pain after Osteoporotic Vertebral Body Fracture.

Endplate Deficits and Posterior Wall Injury Are Predictive of Prolonged Back Pain after Osteoporotic Vertebral Body Fracture.
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DOI:
10.22603/ssrr.2021-0101
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发表时间:
2022
影响因子:
1.2
通讯作者:
Nakagawa Y
Nakagawa Y
中科院分区:
其他
文献类型:
--
作者:
Teraguchi M;Kawakami M;Enyo Y;Kagotani R;Mera Y;Kitayama K;Oka H;Yamamoto Y;Nakagawa M;Nakatani T;Nakagawa Y

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老年人骨质疏松性椎体压缩性骨折(OVCF)是一个主要的公共卫生问题。本回顾性病例对照研究旨在确定放射学、磁共振成像(MRI)和计算机断层扫描(CT)之间观察者间可靠性的差异,以及CT放射学结果是否可以预测OVCF后2周的持续背痛。 根据入院后2周的数字评定量表将患者分为持续性背痛组和恢复性背痛组。X线摄影、MRI和CT图像根据先前分类描述的惯例进行分类。观察者间的可靠性由两名委员会认证的脊柱外科医生评定的图像计算。多变量逻辑回归模型用于评估CT上是否存在前壁损伤、终板缺损、后壁损伤、外侧壁损伤或椎间盘缺损是否可预测长期背痛。 在130例患者中,89例(68.5%)在入院后2周出现持续背痛。无论是平均年龄(分别为79.8岁和80.1岁),还是初次就诊的持续时间(分别为9.4天和6.4天),在长期和恢复性背痛组之间都没有显著差异。X线摄影、MRI和CT的观察者间可靠性分别为0.51、0.77(0.67-0.86)和0.82(0.72-0.92)。 在调整了年龄、性别、初次就诊时间和OVCF程度等混杂因素后,多变量分析显示终板缺损和后壁损伤的存在是持续性背痛的重要预测因素(比值比[OR] 8.5,曲线下面积(AUC); 0.79和OR 2.5,AUC 0.72)。注意到基于CT的评价的可靠性评估良好。在初次就诊时进行详细的新CT评估后,终板缺损和后壁损伤的存在是OVCF后2周持续背痛的重要风险因素。
Osteoporotic vertebral compression fracture (OVCF) in the elderly is a major public health concern. This retrospective case-control study aimed to determine the difference in interobserver reliability between radiography, magnetic resonance imaging (MRI), and computed tomography (CT), respectively, and whether CT radiological findings can predict prolonged back pain at 2 weeks after OVCFs. Patients were divided into the prolonged back pain group or the recovered back pain group depending on the numerical rating scale at 2 weeks after admission. Radiography, MRI, and CT images were classified on the basis of conventions described by previous classifications. Interobserver reliability was calculated on images rated by two board-certified spine surgeons. Multivariate logistic regression models were used to evaluate whether the presence or absence of anterior wall injury, endplate deficit, posterior wall injury, lateral wall injury, or intervertebral disc deficit on CT was predictive of prolonged back pain. Of the 130 patients, 89 cases (68.5%) involved prolonged back pain at 2 weeks after admission. Neither average age (79.8 vs. 80.1 years, respectively) nor duration to initial consultation (9.4 vs. 6.4 days, respectively) differed significantly between the prolonged and recovered back pain groups. Interobserver reliability was 0.51, 0.77 (0.67-0.86), and 0.82 (0.72-0.92) for radiography, MRI, and CT, respectively. After adjusting for confounding factors such as age, sex, duration to initial consultation, and extent of OVCF, the multivariate analysis showed that the presence of endplate deficit and posterior wall injury was a significant predictive factor for prolonged back pain (odds ratio [OR] 8.5, area under the curve (AUC); 0.79 and OR 2.5, AUC 0.72), respectively. Good reliability assessments of CT-based evaluations were noted. After a detailed novel CT evaluation at initial presentation, the presence of an endplate deficit and posterior wall injury was the significant risk factor for prolonged back pain at 2 weeks after an OVCF.
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