Association of tea consumption and cutaneous squamous cell carcinoma.
Association of tea consumption and cutaneous squamous cell carcinoma.
复制标题
茶消耗和皮肤鳞状细胞癌的关联。
DOI：
10.1080/01635581.2011.523496
复制
发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Chren MM
中科院分区：
文献类型：
--
作者：
Asgari MM;White E;Warton EM;Hararah MK;Friedman GD;Chren MM
实验室和流行病学研究表明，喝茶对皮肤鳞状细胞癌（SCC）的风险具有保护作用。我们设计了一项病例对照研究，使用大型健康维护组织人群来检查推定的保护性暴露（包括喝茶）与SCC风险之间的关联。病例（n= 415）定义为2004年病理证实患有SCC的Kaiser Permanente北方加州（KPNC）成员，对照组（n=415）为年龄、性别和种族匹配的成员，既往无皮肤癌病史。通过问卷调查确定饮茶量和SCC危险因素。使用条件logistic回归计算比值比（OR）和95%置信区间（CI），以估计SCC与定期使用以及饮茶剂量和持续时间的相关性。风险因素调整模型包括教育，吸烟，头发和眼睛的颜色，皮肤类型，皮肤癌家族史和雀斑，晒伤，阳光照射和晒黑床使用的历史。调整后的分析显示，经常喝茶不会降低SCC风险（OR=1.11，95%CI：0.81-1.54）。检查持续时间、剂量以及合并的持续时间和剂量暴露变量未改变结果。我们没有发现喝茶与皮肤SCC风险相关的证据。
Laboratory and epidemiologic studies suggest a protective effect of tea consumption on risk of cutaneous squamous cell carcinoma (SCC). We designed a case-control study to examine the association between putative protective exposures, including tea consumption, and SCC risk using a large health maintenance organization population. Cases (n= 415) were defined as Kaiser Permanente Northern California (KPNC) members with a pathology-verified SCC in 2004 and controls (n=415) were age-, gender, and race-matched members with no previous history of skin cancer. Tea consumption and SCC risk factors were ascertained by questionnaire. Odds ratios (OR) and 95% confidence intervals (CI) were calculated using conditional logistic regression to estimate the association of SCC with regular use, as well as dose and duration of tea consumption. Risk factor adjusted models included education, smoking, hair and eye color, skin type, family history of skin cancer and history of freckling, sunburns, sun exposure and tanning bed use. Adjusted analyses showed no reduction in SCC risk with regular consumption of tea (OR=1.11, 95% CI: 0.81–1.54). Examining duration, dose, and combined duration and dose exposure variables did not alter findings. We found no evidence that tea consumption was associated with cutaneous SCC risk.
影响因子：
13.8
作者：
Rees, Judy R.;Stukel, Therese A.;Karagas, Margaret R.
通讯作者：
Karagas, Margaret R.
影响因子：
12.7
作者：
KRIEGER, N
通讯作者：
KRIEGER, N
影响因子：
5
作者：
Satia-Abouta, J;Patterson, RE;White, E
通讯作者：
White, E