Comparison of the flashlamp pulsed dye laser with the argon tunable dye laser with robotized handpiece for facial telangiectasia
Comparison of the flashlamp pulsed dye laser with the argon tunable dye laser with robotized handpiece for facial telangiectasia
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闪光灯脉冲染料激光器与带有机器人手机的氩可调谐染料激光器治疗面部毛细血管扩张的比较
DOI：
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发表时间：
1993
影响因子：
2.4
通讯作者：
M. Goodman
中科院分区：
文献类型：
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作者：
Maria Ross;Melissa A. Watcher;M. Goodman
这项前瞻性研究比较了闪光灯脉冲染料激光 (FPDL) 与带有机器人手机的氩可调谐染料激光 (ATDL/H) 治疗面部毛细血管扩张的疗效、副作用和患者接受度。招募了 17 名患有双侧对称面部毛细血管扩张的成年患者。每位患者的右脸颊均使用 FPDL 进行一次治疗，能量密度为 6.0-6.75 J/cm2，光斑尺寸为 5 毫米。左脸颊在同一疗程中使用 ATDL/H 进行治疗，功率为 1 W，能量密度为 26-27 J/cm2，六角形治疗区域为 13 毫米（由手机机械分组的 127 个单独的 1 毫米点）。研究人员在第 2、4 和 6 周对患者进行主观评估，评估患者的起泡、肿胀、瘀伤、色素变化、疤痕、总体疗效和患者偏好。 FPDL 的平均治疗时间为 5.4 分钟，ATDL/H 的平均治疗时间为 9.4 分钟。到第 2 周时，所有患者两侧的起泡、结痂和不适均完全消失。所有 FPDL 患者均出现瘀伤，但 62.5% 的患者在 2 周时消退，100% 在 4 周时消退。 ATDL/H 没有瘀伤。 FPDL 的炎症后色素沉着过度更为突出，但到第 6 周，88% 的病例已得到解决。根据研究人员的评估，100% 的 FPDL 治疗区域显示出出色的毛细血管扩张清除率，而 ATDL/H 治疗区域的清除率为 47%。尽管 FPDL 在一种治疗中清除面部毛细血管扩张的效果更好，但在 15 名有偏好的患者中，47% 更喜欢 ATDL/H，因为 FPDL 会出现明显的瘀伤。总之，虽然 FPDL 显示出更大的客观疗效，但可接受的疗效加上没有瘀伤，导致几乎一半的患者更喜欢 ATDL/H 治疗。 © 1993 Wiley-Liss, Inc.
This prospective study compares the efficacy, side effects, and patient acceptance of the flashlamp pulsed dye laser (FPDL) with the argon tunable dye laser with robotized handpiece (ATDL/H) for facial telangiectasias. Seventeen adult patients with bilaterally symmetric facial telangiectasias were enrolled. The right cheek on each patient was treated in one session with the FPDL at a fluence of 6.0–6.75 J/cm2 and a spot size of 5 mm. The left cheek was treated at the same session with the ATDL/H at a power of 1 W, a fluence of 26–27 J/cm2, and a hexagonal treatment area of 13 mm (127 individual 1 mm spots grouped mechanically by the handpiece). Patients were evaluated subjectively and by the investigators at 2, 4, and 6 weeks for blistering, swelling, bruising, changes in pigment, scarring, overall efficacy, and patient preference. Average treatment times were 5.4 minutes for FPDL and 9.4 minutes for ATDL/H. Blistering, crusting, and discomfort were completely resolved on both sides by week 2 in all patients. Bruising occurred in all patients with FPDL but had resolved in 62.5% of patients at 2 weeks and 100% at 4 weeks. There was no bruising with ATDL/H. Postinflammatory hyper‐pigmentation was much more prominent with FPDL but had resolved in 88% of cases by week 6. As rated by the investigators 100% of the FPDL treated areas showed excellent clearing of telangiectasias, compared with 47% of ATDL/H treated areas. Despite better efficacy of the FPDL in clearing facial telangiectasias in one treatment, of the 15 patients with a preference 47% preferred the ATDL/H due to the marked bruising experienced with the FPDL. In conclusion, although the FPDL showed greater objective efficacy, the acceptable efficacy combined with the lack of bruising led almost half of the patients to prefer treatment with the ATDL/H. © 1993 Wiley‐Liss, Inc.
可调谐染料（577 nm）激光和氩激光的比较组织学研究：染料激光的特定血管效应。
DOI：
10.1111/1523-1747.ep12482476
发表时间：
1981
期刊：
The Journal of investigative dermatology
影响因子：
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作者：
Greenwald,J;Rosen,S;Anderson,RR;Harrist,T;MacFarland,F;Noe,J;Parrish,JA
通讯作者：
Parrish,JA