Delivery of nanomedicines to extracellular and intracellular compartments of a solid tumor.
Delivery of nanomedicines to extracellular and intracellular compartments of a solid tumor.
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DOI:
10.1016/j.addr.2011.04.006
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发表时间:
2012-01
影响因子:
16.1
通讯作者:
Au, Jessie L. -S.
中科院分区:
文献类型:
--
作者:
Li, Yinghuan;Wang, Jie;Wientjes, M. Guillaume;Au, Jessie L. -S.
关键词:
Advances in molecular medicines have led to identification of promising targets on cellular and molecular levels. These targets are located in extracellular and intracellular compartments. The latter include cytosol, nucleus, mitochondrion, Golgi apparatus and endoplasmic reticulum. This report gives an overview on the barriers to delivering nanomedicines to various target sites within a solid tumor, the experimental approaches to overcome such barriers, and the potential utility of nanotechnology.
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影响因子:
4.2
作者:
Bode, Christian;Trojan, Lutz;Michel, Maurice Stephan
通讯作者:
Michel, Maurice Stephan
影响因子:
3.4
作者:
Dos Santos, Nancy;Allen, Christine;Bally, Marcel B.
通讯作者:
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影响因子:
4.7
作者:
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Thompson, David H.
DOI:
10.1016/0005-2736(85)90244-5
发表时间:
1985-01-01
期刊:
BIOCHIMICA ET BIOPHYSICA ACTA
影响因子:
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作者:
DIJKSTRA, J;VANGALEN, M;SCHERPHOF, G
通讯作者:
SCHERPHOF, G
影响因子:
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作者:
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通讯作者:
Dykxhoorn, Derek M.