In vivo tibiofemoral cartilage deformation during the stance phase of gait.
In vivo tibiofemoral cartilage deformation during the stance phase of gait.
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DOI：
10.1016/j.jbiomech.2009.10.028
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发表时间：
2010-03-03
影响因子：
2.4
通讯作者：
Li, Guoan
中科院分区：
文献类型：
--
作者：
Liu, Fang;Kozanek, Michal;Hosseini, Ali;Van de Velde, Samuel K.;Gill, Thomas J.;Rubash, Harry E.;Li, Guoan
了解膝关节软骨接触生物力学对了解关节功能和软骨病理具有重要意义。然而，体内胫股关节软骨在步态过程中的接触生物力学仍不清楚。本研究的目的是测定跑步机步态站立阶段体内胫股软骨接触的生物力学。8个健康膝关节在跑步机上行走时，用双透视系统进行磁共振扫描和成像。根据MR图像构建胫骨、股骨及相关软骨，并结合双透视图像确定步态站立阶段体内软骨接触变形。在整个步态站立阶段，最大的间隔室接触变形量在静息软骨厚度的7%至23%之间，并发生在软骨较厚的区域。与外侧室相比，胫股内侧室在前后方向的偏移量更大。在整个站立阶段，内侧间隔室的接触面积大于外侧间隔室。在体胫股软骨在步态过程中接触生物力学的信息可以为软骨的体外测试提供生理边界。此外，关于非患病膝盖在步态过程中变形的位置和大小的数据可以识别患病膝盖可能发生负荷和后来的损伤的位置。
The knowledge of articular cartilage contact biomechanics in the knee joint is important for understanding the joint function and cartilage pathology. However, the in-vivo tibiofemoral articular cartilage contact biomechanics during gait remains unknown. The objective of this study was to determine the in vivo tibiofemoral cartilage contact biomechanics during the stance phase of treadmill gait. Eight healthy knees were magnetic resonance (MR) scanned and imaged with a dual fluoroscopic system during gait on a treadmill. The tibia, femur and associated cartilage were constructed from the MR images and combined with the dual fluoroscopic images to determine in vivo cartilage contact deformation during the stance phase of gait. Throughout the stance phase of gait, the magnitude of peak compartmental contact deformation ranged between 7% and 23% of the resting cartilage thickness and occurred at regions with thicker cartilage. Its excursions in the anteroposterior direction were greater in the medial tibiofemoral compartment as compared to those in the lateral compartment. The contact areas throughout the stance phase were greater in the medial compartment than in the lateral compartment. The information on in vivo tibiofemoral cartilage contact biomechanics during gait could be used to provide physiological boundaries for in vitro testing of cartilage. Also, the data on location and magnitude of deformation among non-diseased knees during gait could identify where loading and later injury might occur in diseased knees.
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影响因子：
2.4
作者：
Kozanek, Michal;Hosseini, Ali;Liu, Fang;Van de Velde, Samuel K.;Gill, Thomas J.;Rubash, Harry E.;Li, Guoan
通讯作者：
Li, Guoan
影响因子：
2.4
作者：
LAFORTUNE, MA;CAVANAGH, PR;KALENAK, A
通讯作者：
KALENAK, A
影响因子：
2.4
作者：
ATESHIAN, GA;SOSLOWSKY, LJ;MOW, VC
通讯作者：
MOW, VC
影响因子：
7
作者：
Cohen, ZA;McCarthy, DM;Ateshian, GA
通讯作者：
Ateshian, GA
影响因子：
2.8
作者：
Dyrby, CO;Andriacchi, TP
通讯作者：
Andriacchi, TP