Surface plasmon resonance imaging of cell-substrate contacts with radially polarized beams.
Surface plasmon resonance imaging of cell-substrate contacts with radially polarized beams.
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DOI:
10.1364/oe.16.020734
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发表时间:
2008-12-08
期刊:
影响因子:
3.8
通讯作者:
Gao BZ
中科院分区:
文献类型:
--
作者:
Moh KJ;Yuan XC;Bu J;Zhu SW;Gao BZ
We demonstrate the proof-of-concept for surface plasmon resonance sensing and imaging via a virtual probe at the cell-substrate interface of a biological cell in aqueous media. The technique is based on the optical excitation by focused radially polarized beams of localized surface plasmons, which forms a virtual probe on the metal substrate. The intensity distribution at the back focal plane of the objective lens enables quantitative measurements to be made of the cell-substrate contact. The acquired data is then visualized in the form of a local refractive index map.
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影响因子:
8.6
作者:
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通讯作者:
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DOI:
10.1046/j.1365-2818.2003.01163.x
发表时间:
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期刊:
JOURNAL OF MICROSCOPY-OXFORD
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