Phenotypic plasticity and developmental innovations in nematodes.

Phenotypic plasticity and developmental innovations in nematodes.
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线虫的表型可塑性和发育创新。

DOI:
10.1016/j.gde.2016.05.018
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发表时间:
2016
影响因子:
4
通讯作者:
Tandonnet S
Tandonnet S
中科院分区:
生物学2区
文献类型:
--
作者:
Tandonnet S

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发育可塑性被认为是表型多样化的促进者,但控制它的分子机制在很大程度上是未知的。我们回顾了最近的比较分析,在非小杆线虫,显示多型幼虫发育,嘴的形态和生殖模式。未来的一些挑战将是在分子水平和生态水平上将这些表型性状如何相互联系起来。这将需要对几种线虫物种进行采样,对其生态进行表征,并利用经典遗传学和最近开发的技术进步,如基因组编辑。
Developmental plasticity has been implicated as a facilitator for phenotypic diversification, but the molecular mechanisms controlling it are largely unknown. We review recent comparative analyses in non-Caenorhabditis nematodes that display polyphenisms in larval development, mouth morphology and reproductive mode. Some of the challenges ahead will be to connect how these phenotypic traits are linked to each other at the molecular level, and at the ecological level. This will require sampling of several nematode species, the characterization of their ecology and the employment of both classical genetics and recently developed technological advances, such as genome editing.
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