Associations of Socio-Demographic, Clinical and Biochemical Parameters with Healthcare Cost, Health- and Renal-Related Quality of Life in Hemodialysis Patients: A Clinical Observational Study.

Associations of Socio-Demographic, Clinical and Biochemical Parameters with Healthcare Cost, Health- and Renal-Related Quality of Life in Hemodialysis Patients: A Clinical Observational Study.
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DOI:
10.3390/ijerph17186552
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发表时间:
2020-09-09
影响因子:
--
通讯作者:
Duong TV
Duong TV
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Doan KVD;Nguyen HTM;Nguyen NTH;Dang KC;Yang SH;Duong TV

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我们研究了与血液透析患者的医疗费用、健康相关生活质量(HRQOL)和肾脏疾病生活质量(KDQOL)相关的因素。我们于2019年1月至4月在血液透析中心对160名患者进行了横断面研究。评估了社会人口统计学、临床和实验室参数以及生活质量(QOL)(使用KDQOL-SF-v1.3)。每月医疗费用从医院信息系统中提取。医疗费用、HRQOL和KDQOL的平均值分别为9.4 ± 160万越南盾、45.1 ± 21.9越南盾和51.3 ± 13.0越南盾。在多变量分析中,血液透析年限较长的患者的医疗费用较高(回归系数(B):0.74; 95%置信区间(95% CI):0.25; 1.23),合并症(B:0.77; 95% CI:0.24; 1.31);红细胞压积浓度较高的患者较低(B:-0.07; 95% CI:-0.13;-0.01)。生活在城市地区的患者(B:9.08; 95% CI:2.30; 15.85)的HRQOL较好;合并症患者(B:−14.20; 95% CI:−21.43; −6.97)和低白蛋白血症患者(B:−9.31; 95% CI:−16.58; −2.04)的HRQOL较差。受教育程度高的患者(B:5.38~6.29)KDQOL较好;合并症患者KDQOL较差(B:-6.17; 95%CI:-10.49;-1.85)。总之,较长的血液透析年份、合并症和较低的红细胞压积浓度与较高的医疗费用相关。居住在城市地区的患者有更好的HRQOL和更高的教育水平导致更好的KDQOL。合并症患者的HRQOL和KDQOL较低。营养不良患者的HRQOL较低。
We examined factors associated with healthcare cost, health-related quality of life (HRQOL), and kidney disease quality of life (KDQOL) in hemodialysis patients. We conducted a cross-sectional study on 160 patients from January to April 2019 at a hemodialysis center. Socio-demographic, clinical, and laboratory parameters and quality of life (QOL) (using KDQOL-SF-v1.3) were assessed. Monthly healthcare costs were extracted from the hospital information system. The means of healthcare cost, HRQOL, and KDQOL were VND 9.4 ± 1.6 million, VND 45.1 ± 21.9 and VND 51.3 ± 13.0, respectively. In the multivariate analysis, the healthcare cost was higher in patients with a longer hemodialysis vintage (regression coefficient (B): 0.74; 95% confidence interval (95% CI): 0.25; 1.23), comorbidity (B: 0.77; 95% CI: 0.24; 1.31); and lower in those with a higher hematocrit concentration (B: −0.07; 95% CI: −0.13; −0.01). Patients that lived in urban areas (B: 9.08; 95% CI: 2.30; 15.85) had a better HRQOL; those with a comorbidity (B: −14.20; 95% CI: −21.43; −6.97), and with hypoalbuminemia (B: −9.31; 95% CI: −16.58; −2.04) had a poorer HRQOL. Patients with a higher level of education (B: 5.38~6.29) had a better KDQOL; those with a comorbidity had a poorer KDQOL (B: −6.17; 95% CI: −10.49; −1.85). In conclusion, a longer hemodialysis vintage, a comorbidity and a lower hematocrit concentration were associated with higher healthcare costs. Patients who lived in urban areas had a better HRQOL and a higher level of education led to a better KDQOL. Patients with a comorbidity had a lower HRQOL and KDQOL. Malnourished patients had a lower HRQOL.
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