Cravings for alcohol in alcohol use disorders are associated with attention deviation to alcohol: An observational study of Japanese in-patients.

Cravings for alcohol in alcohol use disorders are associated with attention deviation to alcohol: An observational study of Japanese in-patients.
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DOI:
10.1097/md.0000000000033222
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发表时间:
2023-03-10
期刊:
影响因子:
1.6
通讯作者:
--
中科院分区:
医学4区
文献类型:
--
作者:

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酒精使用障碍(AUD)可能与酒精相关信息的注意偏倚(AB)增加有关。因此,我们的目的是探讨酒精相关性AB、渴望和治疗后AUD患者复发风险之间的关系。研究组包括24名完成酒精戒断管理的住院AUD患者。AB使用基于图像的任务进行评估,参与者被要求尽可能快、准确地选择不含酒精的图像,并测量反应时间(RT)。使用100毫米视觉模拟量表评估饮酒欲望的强度,使用酒精复发风险量表评估复发风险。使用线性回归评估这些变量之间的关系,以年龄、性别、住院时间和抑郁评分作为协变量。渴望强度与AB RT (R2 = 0.625)和饮酒行为复发风险(酒精复发风险量表评分,R2 = 0.64)显著相关。性别和γ-GTP是确定关系的显著解释变量。本研究的主要局限性是我们研究组中男性的比例高于女性,并且缺乏用于AB RTs基线比较的对照组。本研究结果提示AUD患者饮酒欲望与AB相关,饮酒欲望强度与AUD治疗后饮酒行为复发的风险相关。
Alcohol use disorder (AUD) may be associated with increased attentional bias (AB) toward alcohol-related information. Accordingly, our aim was to explore the relationships between alcohol-related AB, cravings, and risk of relapse among individuals with AUD after treatment. The study group included 24 in-patients with AUD who had completed alcohol withdrawal management. AB was evaluated using an image-based task, with participants asked to select the nonalcoholic image as fast and as accurately as possible and the response time (RT) measured. The intensity of the desire to drink was evaluated using a 100-mm Visual Analog Scale and the risk of relapse using the Alcohol Relapse Risk Scale. Linear regression was used to evaluate the relationship between these variables, with age, gender, duration of hospitalization, and depression score used as covariates. Intensity of cravings was significantly associated with AB RT (R2 =.625) and risk of relapse of drinking behavior (Alcohol Relapse Risk Scale score, R2 =.64). Gender and γ-GTP were significant explanatory variables of identified relationships. The main limitations of our study are a higher proportion of men than women in our study group and the absence of a control group for baseline comparison of AB RTs. This study results suggested that the desire to drink is related to AB among patients with AUD and that the intensity of the desire to drink is related to the risk of a relapse in drinking behavior after AUD treatment.
DOI: 10.1037/pha0000018
发表时间: 2015-06
影响因子: 2.3
作者:
Ramirez, Jason J.;Monti, Peter M.;Colwill, Ruth M.
通讯作者: Colwill, Ruth M.