The economic value of targeting aging.
The economic value of targeting aging.
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DOI：
10.1038/s43587-021-00080-0
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发表时间：
2021-07
期刊：
影响因子：
--
通讯作者：
Sinclair, David A. A.
中科院分区：
文献类型：
--
作者：
Scott, Andrew J. J.;Ellison, Martin;Sinclair, David A. A.
预期寿命的发展以及对生物和“健康”老龄化的日益重视，为健康科学家和经济学家提出了许多重要问题。是通过减少发病率来使生活更健康，还是通过延长寿命来使生活更长久？与根除特定疾病的努力相比，针对老龄化本身有什么好处？在这里，我们分析了现有的数据，以评估预期寿命增加，健康改善和针对衰老的治疗的经济价值。我们表明，降低发病率以改善健康状况比进一步延长预期寿命更有价值，而且针对老龄化可能比根除个别疾病带来更大的经济收益。我们发现，老龄化的减缓使预期寿命增加1年的价值为38万亿美元，增加10年的价值为367万亿美元。最终，在改善我们衰老方面取得的进展越多，进一步改善的价值就越大。一项经济分析表明，与根除个别疾病相比，瞄准老龄化可能带来更大的经济收益。减缓老龄化以增加1年的预期寿命价值38万亿美元，增加10年则为367万亿美元。
Developments in life expectancy and the growing emphasis on biological and ‘healthy’ aging raise a number of important questions for health scientists and economists alike. Is it preferable to make lives healthier by compressing morbidity, or longer by extending life? What are the gains from targeting aging itself compared to efforts to eradicate specific diseases? Here we analyze existing data to evaluate the economic value of increases in life expectancy, improvements in health and treatments that target aging. We show that a compression of morbidity that improves health is more valuable than further increases in life expectancy, and that targeting aging offers potentially larger economic gains than eradicating individual diseases. We show that a slowdown in aging that increases life expectancy by 1 year is worth US$38 trillion, and by 10 years, US$367 trillion. Ultimately, the more progress that is made in improving how we age, the greater the value of further improvements. An economic analysis suggests that targeting aging offers potentially larger economic gains than eradicating individual diseases. Slowing aging to increase life expectancy by 1 year is worth US$38 trillion, and by 10 years, US$367 trillion.
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影响因子：
64.8
作者：
Lu Y;Brommer B;Tian X;Krishnan A;Meer M;Wang C;Vera DL;Zeng Q;Yu D;Bonkowski MS;Yang JH;Zhou S;Hoffmann EM;Karg MM;Schultz MB;Kane AE;Davidsohn N;Korobkina E;Chwalek K;Rajman LA;Church GM;Hochedlinger K;Gladyshev VN;Horvath S;Levine ME;Gregory-Ksander MS;Ksander BR;He Z;Sinclair DA
通讯作者：
Sinclair DA
影响因子：
8
作者：
Johnson, RW;Neumark, D
通讯作者：
Neumark, D
DOI：
10.1111/j.1542-4774.2012.01101.x
发表时间：
2013-01-01
影响因子：
3.6
作者：
Finkelstein, Amy;Luttmer, Erzo F. P.;Notowidigdo, Matthew J.
通讯作者：
Notowidigdo, Matthew J.
影响因子：
3.5
作者：
Abeliansky, Ana Lucia;Strulik, Holger
通讯作者：
Strulik, Holger
影响因子：
29
作者：
Barzilai N;Crandall JP;Kritchevsky SB;Espeland MA
通讯作者：
Espeland MA