Validating a brief screening measure for early-onset substance use during adolescence in a diverse, nationwide birth cohort.
Validating a brief screening measure for early-onset substance use during adolescence in a diverse, nationwide birth cohort.
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DOI：
10.1016/j.addbeh.2022.107277
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发表时间：
2022-06
影响因子：
4.4
通讯作者：
Meier, Madeline H.
中科院分区：
文献类型：
--
作者：
Pelham, William E., III;Corbin, William R.;Meier, Madeline H.
洛伯风险评分 (LRS) 的开发是为了预测从童年晚期到青春期的早发性大麻使用情况，从而促进早期识别。然而，LRS 是在不具有代表性的历史样本中开发的，因此不确定其是否适用于当今美国各地的儿童/青少年。我们在一个多元化的全国性队列 (N=4,898) 中对 LRS 进行了外部验证，该队列根据美国人口普查的构成进行加权。 20 个城市的参与者在青少年大约 5 岁、9 岁和 15 岁时完成了评估。父母在 ~5 岁和 ~9 岁时完成了 LRS 访谈。在约 15 岁的采访中，青少年报告了 15 岁之前开始酗酒/吸毒、14-16 岁时每月饮酒/酗酒以及 14-16 岁时每月多次吸食大麻的情况。首先，我们验证了约 9 岁时测量的 LRS。 15 岁之前开始使用大麻的受试者工作曲线下面积为 0.62，15 岁之前开始使用香烟的受试者工作曲线下面积为 0.68，14-16 岁每月多次使用大麻的受试者工作曲线下面积为 0.62。对于饮酒结果，LRS 表现无法与机会预测区分开来。建议的 LRS≥2 筛查截止点确定了 24% 的儿童，其中早发性大麻/香烟使用结果的发生频率是一般人群的 1.4-2.2 倍。 LRS 的表现并没有因性别、种族或民族而存在显着差异。当 LRS 在大约 5 岁时测量时，某些结果的 AUROC 显着较低。总之，研究结果支持 LRS 测量作为识别儿童早期或晚期儿童在青春期早发吸毒风险的潜在工具。
The Loeber Risk Score (LRS) was developed to predict early-onset cannabis use in adolescence from late childhood, facilitating early identification. However, the LRS was developed in non-representative historical samples, leaving uncertain its generalizability to children/adolescents across the U.S. today. We externally validated the LRS in a diverse, nationwide cohort (N=4,898) weighted to the composition of the U.S. Census. Participants in 20 cities completed assessments when youth were approximately 5, 9, and 15 years old. Parents completed the LRS at the age ~5 and ~9 interviews. At the age ~15 interview, youth reported on the onset of alcohol/drug use before age 15, monthly drinking/binge drinking at ages 14-16, and use of cannabis multiple times per month at ages 14-16. First, we validated the LRS measured at age ~9. Area under the receiver operating curve was 0.62 for onset of cannabis use before age 15,0.68 for onset of cigarette use before age 15, and 0.62 for use of cannabis multiple times per month at ages 14-16. For drinking outcomes, LRS performance could not be distinguished from chance prediction. The recommended screening cutoff of LRS≥2 identified 24% of children, among whom early-onset cannabis/cigarette use outcomes occurred 1.4-2.2 times more frequently than the general population. The LRS’ performance did not vary significantly by sex, race, or ethnicity. When the LRS was measured at age ~5, AUROC was significantly lower for some outcomes. Together, findings support the LRS measure as a potential tool for identifying children in early or late childhood at risk of early-onset drug use in adolescence.
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影响因子：
3.5
作者：
Hawkins, JD;Van Horn, ML;Arthur, MW
通讯作者：
Arthur, MW
DOI：
10.1007/s40865-021-00165-9
发表时间：
2021-04-28
影响因子：
1.9
作者：
Ahonen, Lia;Farrington, David P.;Stouthamer-Loeber, Magda
通讯作者：
Stouthamer-Loeber, Magda
影响因子：
4.2
作者：
Boccio, Cashen M.;Jackson, Dylan B.
通讯作者：
Jackson, Dylan B.
影响因子：
4.7
作者：
Loeber R;Clark DB;Ahonen L;FitzGerald D;Trucco EM;Zucker RA
通讯作者：
Zucker RA
影响因子：
6
作者：
Kuntsche, Emmanuel;Rossow, Ingeborg;Kuntsche, Sandra
通讯作者：
Kuntsche, Sandra