HIV-associated immune dysfunction and viral infection: role in the pathogenesis of AIDS-related lymphoma.
HIV-associated immune dysfunction and viral infection: role in the pathogenesis of AIDS-related lymphoma.
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DOI：
10.1007/s12026-010-8168-8
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发表时间：
2010-12
影响因子：
4.4
通讯作者：
Martinez-Maza, Otoniel
中科院分区：
文献类型：
--
作者：
Epeldegui, Marta;Vendrame, Elena;Martinez-Maza, Otoniel
关键词：
HIV infection is associated with a much higher risk for the development of non-Hodgkin lymphoma (AIDS-NHL). The principal causes of lymphomagenesis in HIV-infected individuals are thought to be the loss of immune function seen in HIV infection, which results in the loss of immunoregulation of Epstein–Barr virus-infected B cells, as well as HIV infection-associated immune dysregulation, including chronic B-cell activation. In this review, we discuss recent reports that further support the importance of these factors, and we highlight emerging evidence of different mechanisms that potentially drive lymphomagenesis in HIV-infected individuals.
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影响因子：
8.6
作者：
Breen, EC;Boscardin, WJ;Martínez-Maza, O
通讯作者：
Martínez-Maza, O
DOI：
10.1084/jem.170.6.2081
发表时间：
1989-12-01
期刊：
The Journal of experimental medicine
影响因子：
--
作者：
Fiorentino DF;Bond MW;Mosmann TR
通讯作者：
Mosmann TR
影响因子：
5.4
作者：
Esser, MT;Graham, DR;Lifson, JD
通讯作者：
Lifson, JD
影响因子：
3.6
作者：
Gil, Yaniv;Levy-Nabot, Sarah;Laskov, Reuven
通讯作者：
Laskov, Reuven
DOI：
10.1093/jnci/djm010
发表时间：
2007-06-20
期刊：
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子：
--
作者：
Biggar, Robert J.;Chaturvedi, Anil K.;Engels, Eric A.
通讯作者：
Engels, Eric A.