Neural Probe with Multiple Optical Stimulation in Depth Direction
Neural Probe with Multiple Optical Stimulation in Depth Direction
复制标题
深度方向多重光学刺激的神经探针
DOI：
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发表时间：
2017
期刊：
影响因子：
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通讯作者：
Y. Haga
中科院分区：
文献类型：
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作者：
Shunsuke Tamaki;T. Matsunaga;Toshinobu Kuki;H. Mushiake;Yoshihito Furusawa;Y. Haga
摘要
本文利用光遗传学技术研制了一种具有8个记录区和3个光发射点的管状神经探头，用于神经电路分析。管的外径为360μm，记录区和光发射点沿深度方向布置。光发射点可以分别刺激不同深度区域的神经元。我们在活体实验中演示了神经元的记录和刺激。结果，该探头在所有的光发射点都有光诱导的神经活动。
SUMMARY
In this paper, tube-shaped neural probe that has eight recording areas and three optical emitting points using with optogenetics technique for neural circuit analysis has been developed. Outer diameter of tube is 360 μm, the recording areas and the optical emitting points arranged in a depth direction. The optical emitting points make it possible to stimulate neurons in various depth areas respectively. We demonstrated the recording and stimulating of neurons in vivo experiment. As the result, the probe got light-induced neural activities at all the optical emitting points.
影响因子：
2.5
作者：
Stark, Eran;Koos, Tibor;Buzsaki, Gyoergy
通讯作者：
Buzsaki, Gyoergy
影响因子：
3.6
作者：
Zorzos AN;Boyden ES;Fonstad CG
通讯作者：
Fonstad CG