A cross-sectional study examining associations between substance use frequency, problematic use and STIs among youth living with HIV.
A cross-sectional study examining associations between substance use frequency, problematic use and STIs among youth living with HIV.
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DOI：
10.1136/sextrans-2017-053334
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发表时间：
2018-06
影响因子：
3.6
通讯作者：
Adolescent Medicine Trials Network for HIV/AIDS Intervention
中科院分区：
文献类型：
--
作者：
Gamarel KE;Nichols S;Kahler CW;Westfall AO;Lally MA;Wilson CM;Adolescent Medicine Trials Network for HIV/AIDS Intervention
这项研究试图探查性传播感染的流行率，以及药物使用频率和/或有问题的使用--特别是酒精、大麻和其他药物--是否与艾滋病毒携带者中的性传播感染诊断有关。通过青少年艾滋病毒干预试验网络，在14个青少年艾滋病毒诊所招募了823名青年艾滋病毒感染者。研究人员在参与者完成包括辅助在内的横断面调查之前，从医疗记录中提取了长达26周的STI数据，该调查衡量了物质使用频率和后果。在基线评估时，近三分之一的年轻人(30.5%)已被诊断为性传播感染。在多变量分析中，每周吸食或更多吸食大麻(aOR=10.66，95%CI：4.39，25.87，p<；0.001)的人被诊断为性传播感染的几率更高。此外，与低危饮酒者相比，符合中度(AOR=5.23，95%CI：2.5，10.93，p<；0.001)和高风险(AOR=6.53，95%CI：1.2，35.68，p<；0.05)酒精使用标准的年轻人被诊断为性传播感染的几率更高。研究结果强调，有必要调查更频繁地使用大麻和有问题的酒精使用在青少年性传播感染发病率中的作用。考虑到在艾滋病毒护理环境中发现的青少年艾滋病毒感染者的性传播感染诊断中药物使用频率和问题使用之间的关联，临床医生应该使用有效的物质使用筛查工具，包括频率和后果，以便确定可能需要进一步评估和治疗的青壮年妇女医院。
This study sought to examine the prevalence of sexually transmitted infections (STIs) and whether substance use frequency and/or problematic use—specifically alcohol, marijuana, and other drugs—was associated with having an STI diagnosis among youth living with HIV (YLWH) A sample of 823 YLWH were recruited at 14 adolescent HIV clinics through the Adolescent Medicine Trials Network for HIV Interventions. Study staff abstracted STI data from medical records for up to 26 weeks prior to participants’ completing a cross-sectional survey including the ASSIST, which measures substance use frequency and consequences. Almost one-third of youth had been diagnosed with an STI (30.5%) at the time of their baseline assessment. In multivariable analyses, those who engaged in weekly or greater marijuana use (AOR=10.66, 95% CI: 4.39, 25.87, p<0.001) had an increased odds of being diagnosed with an STI. Additionally, youth who met alcohol use criteria for moderate (AOR = 5.23, 95% CI: 2.50, 10.93, p<0.001) and high risk (AOR = 6.53, 95% CI: 1.20, 35.68, p<0.05) alcohol use had an increased odds of being diagnosed with an STI compared with low risk alcohol users. Study findings underscore the need to investigate the role of greater frequency of marijuana use and problematic alcohol use in STI incidence among YLWH. Given the associations between both substance use frequency and problematic use in STI diagnoses among youth living with HIV seen in HIV care settings, clinicians should use validated substance use screening tools which capture both frequencies and consequences in order to identify YLWH who may need further evaluation and treatment.
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DOI：
10.1016/j.whi.2010.10.005
发表时间：
2011-03
期刊：
Women's health issues : official publication of the Jacobs Institute of Women's Health
影响因子：
--
作者：
Seth P;Wingood GM;DiClemente RJ;Robinson LS
通讯作者：
Robinson LS
影响因子：
158.5
作者：
WU, TC;TASHKIN, DP;ROSE, JE
通讯作者：
ROSE, JE
影响因子：
4.9
作者：
Mustanski, Brian;Byck, Gayle R.;Dick, Danielle
通讯作者：
Dick, Danielle
影响因子：
4.2
作者：
Bruce D;Kahana SY;Bauermeister JA;Nichols SL;Hightow-Weidman LB;Heinze JE;Shea J;Fernández MI;Adolescent Medicine Trials Network for HIV/AIDS Interventions
通讯作者：
Adolescent Medicine Trials Network for HIV/AIDS Interventions
DOI：
10.1016/j.jaac.2010.05.017
发表时间：
2010-10
影响因子：
13.3
作者：
Merikangas KR;He JP;Burstein M;Swanson SA;Avenevoli S;Cui L;Benjet C;Georgiades K;Swendsen J
通讯作者：
Swendsen J