Young Men Who Have Sex with Men at High Risk for HIV, Bangkok MSM Cohort Study, Thailand 2006-2014.

Young Men Who Have Sex with Men at High Risk for HIV, Bangkok MSM Cohort Study, Thailand 2006-2014.
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DOI:
10.1007/s10461-017-1963-7
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发表时间:
2018-07
期刊:
影响因子:
4.4
通讯作者:
Holtz TH
Holtz TH
中科院分区:
医学2区
文献类型:
--
作者:
Thienkrua W;van Griensven F;Mock PA;Dunne EF;Raengsakulrach B;Wimonsate W;Howteerakul N;Ungsedhapand C;Chiwarakorn A;Holtz TH

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据报道,在北美和西欧,与男性发生性关系的年轻男性(YMSM)的艾滋病毒发病率很高,但东南亚的数据有限,表明MSM可能是该地区艾滋病毒流行的驱动因素。我们描述了在泰国曼谷进行的一项队列研究中494名YMSM的HIV发病率和危险因素。艾滋病毒感染率为每100人年7.4例。在多变量分析中,报告使用勃起功能障碍药物联合俱乐部药物,与男性进行接受性或插入性和接受性肛交,甲型肝炎感染,直肠沙眼衣原体感染,HIV血清转换前感染B型肝炎,以及报告与男性稳定伴侣不总是使用避孕套与YMSM中的HIV发病率显著相关。减少YMSM中的艾滋病毒新感染对于实现泰国和该区域设定的目标至关重要。
High HIV incidence has been reported in young men who have sex with men (YMSM) in North America and Western Europe, but there are limited data from Southeast Asia suggesting MSM may be the driver of the HIV epidemic in this region. We described HIV incidence and risk factors among 494 YMSM enrolled in a cohort study in Bangkok, Thailand. The HIV incidence was 7.4 per 100 person-years. In multivariable analysis, reporting use of an erectile dysfunction drug in combination with club drugs, having receptive or both insertive and receptive anal intercourse with men, having hepatitis A infection, having rectal Chlamydia trachomatis, having hepatitis B infection prior to HIV seroconversion, and reporting not always using condoms with male steady partners were significantly associated with HIV incidence in YMSM. Reduction in new HIV infections in YMSM are critical to reach targets set by Thailand and the region.
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