Complex Genomic Rearrangements following Selection in a Glutamine-Limited Medium over Hundreds of Generations.

Complex Genomic Rearrangements following Selection in a Glutamine-Limited Medium over Hundreds of Generations.
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DOI:
10.1128/mra.00729-22
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发表时间:
2022-11-17
影响因子:
0.8
通讯作者:
--
中科院分区:
其他
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在长期进化实验 (LTEE) 中经常观察到大规模基因组变化,包括拷贝数变异 (CNV)。我们之前曾报道过在数百代适应谷氨酰胺限制条件的酿酒酵母种群中检测到复发性 CNV。在这里,我们展示了 7 个 LTEE 菌株及其祖先的全基因组测序 (WGS) 组装。
Large-scale genomic changes, including copy number variations (CNVs), are frequently observed in long-term evolution experiments (LTEEs). We have previously reported the detection of recurrent CNVs in Saccharomyces cerevisiae populations adapting to glutamine-limited conditions over hundreds of generations. Here, we present the whole-genome sequencing (WGS) assemblies of 7 LTEE strains and their ancestor.
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