Simulation Studies of Vestibular Macular Afferent-Discharge Patterns Using a New, Quasi-3-D Finite Volume Method
Simulation Studies of Vestibular Macular Afferent-Discharge Patterns Using a New, Quasi-3-D Finite Volume Method
复制标题
使用新的准 3-D 有限体积方法进行前庭黄斑传入放电模式的模拟研究
DOI：
10.1023/a:1008976030745
复制
发表时间：
2004
影响因子：
1.2
通讯作者：
B. Parnas
中科院分区：
文献类型：
--
作者：
M. Ross;S. Linton;B. Parnas
A quasi-three-dimensional finite-volume numerical simulator was developed to study passive voltage spread in vestibular macular afferents. The method, borrowed from computational fluid dynamics, discretizes events transpiring in small volumes over time. The afferent simulated had three calyces with processes. The number of processes and synapses, and direction and timing of synapse activation, were varied. Simultaneous synapse activation resulted in shortest latency, while directional activation (proximal to distal and distal to proximal) yielded most regular discharges. Color-coded visualizations showed that the simulator discretized events and demonstrated that discharge produced a distal spread of voltage from the spike initiator into the ending. The simulations indicate that directional input, morphology, and timing of synapse activation can affect discharge properties, as must also distal spread of voltage from the spike initiator. The finite volume method has generality and can be applied to more complex neurons to explore discrete synaptic effects in four dimensions.
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影响因子：
2.5
作者：
FERNANDEZ, C;BAIRD, RA;GOLDBERG, JM
通讯作者：
GOLDBERG, JM
影响因子：
2.5
作者：
BAIRD, RA;DESMADRYL, G;GOLDBERG, JM
通讯作者：
GOLDBERG, JM
通过连续切片的透射电子显微照片的三维重建对大鼠黄斑初级传入神经进行区室建模。
影响因子：
2.5
作者：
Chimento,TC;Doshay,DG;Ross,MD
通讯作者：
Ross,MD
海马 CA1 锥体神经元顶端树突中的毒蕈碱调节尖峰反向传播。
DOI：
10.1523/jneurosci.17-15-05782.1997
发表时间：
1997
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Tsubokawa,H;Ross,WN
通讯作者：
Ross,WN