Refining the tobacco dependence phenotype using the Wisconsin Inventory of Smoking Dependence Motives: II. Evidence from a laboratory self-administration assay.
Refining the tobacco dependence phenotype using the Wisconsin Inventory of Smoking Dependence Motives: II. Evidence from a laboratory self-administration assay.
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DOI：
10.1037/a0020235
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发表时间：
2010-08
影响因子：
4.6
通讯作者：
Baker, Timothy B.
中科院分区：
文献类型：
--
作者：
Piasecki, Thomas M.;Piper, Megan E.;Baker, Timothy B.
先前对威斯康星州吸烟依赖动机清单的分析表明，四个子量表作为“主要依赖动机”（PDM），索引了烟草依赖的核心特征，其余子量表反映了“次要依赖动机”（SDM）。当前的研究通过检查 PDM、SDM、它们的子量表以及操作性自我管理范式中的其他依赖指标的相关性来扩展这项工作。吸烟者（N = 58）在不同的固定比例计划下吸烟。分析的重点是预测在烟草获取最小限制条件下的自我管理，以及在严重限制条件下的戒断和渴望。结果支持依赖的双因素模型，其中 PDM 因素与烟草自我管理的关系相对较强，SDM 与戒断症状和痛苦相关的渴望的关系相对较强。 PDM 似乎可以索引烟草依赖的核心特征，但 SDM 可能可以更好地索引对剥夺相关的痛苦和渴望的敏感性。
Prior analyses of the Wisconsin Inventory of Smoking Dependence Motives implicated four subscales as “Primary Dependence Motives” (PDM) indexing the core features of tobacco dependence, with the remaining subscales reflecting “Secondary Dependence Motives” (SDM). The current study extended this work by examining the correlates of PDM, SDM, their subscales, and other indicators of dependence in an operant self-administration paradigm. Smokers (N=58) worked for cigarette puffs under differing fixed ratio schedules. Analyses focused on predicting self-administration under conditions of minimal constraint on tobacco access, and on withdrawal and craving under conditions of severe constraint. Results support a two-factor model of dependence, with the PDM factor showing relatively stronger relations with tobacco self-administration, and SDM showing relatively stronger relations with withdrawal symptomatology and distress-related craving. The PDM appears to index core features of tobacco dependence, but susceptibility to deprivation-contingent distress and craving may be better indexed by SDM.
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DOI：
10.1124/jpet.107.132977
发表时间：
2008-04-01
影响因子：
3.5
作者：
Jackson, K. J.;Martin, B. R.;Damaj, M. I.
通讯作者：
Damaj, M. I.
影响因子：
6
作者：
Madden, GJ;Bickel, WK
通讯作者：
Bickel, WK
影响因子：
4.6
作者：
Piasecki, TM;Fiore, MC;Baker, TB
通讯作者：
Baker, TB
影响因子：
3.8
作者：
Hardin, Jill;He, Yungang;Bergen, Andrew W.
通讯作者：
Bergen, Andrew W.
烟碱乙酰胆碱受体β2亚基基因与基于系统的候选戒烟基因研究有关。
影响因子：
3.5
作者：
Conti, David V.;Lee, Won;Li, Dalin;Liu, Jinghua;Van Den Berg, David;Thomas, Paul D.;Bergen, Andrew W.;Swan, Gary E.;Tyndale, Rachel F.;Benowitz, Neal L.;Lerman, Caryn
通讯作者：
Lerman, Caryn