Injection drug use among street-involved youth in a Canadian setting.
Injection drug use among street-involved youth in a Canadian setting.
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DOI：
10.1186/1471-2458-9-171
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发表时间：
2009-06-03
影响因子：
4.5
通讯作者：
Wood E
中科院分区：
文献类型：
--
作者：
Kerr T;Marshall BD;Miller C;Shannon K;Zhang R;Montaner JS;Wood E
流落街头的年轻人面临着一系列健康和社会挑战，包括血液传播的感染率和死亡率上升。此外，人们越来越关注街头青少年的高风险吸毒问题，特别是注射吸毒问题。我们开展了这项研究，以考察加拿大温哥华街头青少年中注射毒品的流行率和相关风险。从2005年9月至2007年11月，为风险青年研究(ARYS)收集了基线数据，ARYS是加拿大温哥华街头招募的14至26岁青年的预期队列。使用多元Logistic回归，我们比较了有和没有注射病史的年轻人。样本包括560名青年，其中中位年龄为21.9岁，179名(32%)为女性，230名(41.1%)报告曾注射毒品。多因素分析显示：年龄≥为22岁(调整后优势比为1.18，95%CI为1.10~1.28)；性行为相关(优势比为2.17，95%CI为1.35~3.50)；非致死性吸毒过量(调整后优势比为2.10，95%CI为1.38~3.20)；丙型肝炎感染(调整后优势比为22.61，95%CI为7.78~65.70)。这些发现突显了街头青少年中注射毒品的高流行率，令人震惊，并表明其与一系列风险和危害有关，包括性工作参与、吸毒过量和丙型肝炎病毒感染。这些调查结果表明，需要一套广泛的政策和干预措施，以防止开始注射毒品，并解决积极注射的街头青年所面临的风险。
Street-involved youth contend with an array of health and social challenges, including elevated rates of blood-borne infections and mortality. In addition, there has been growing concern regarding high-risk drug use among street-involved youth, in particular injection drug use. We undertook this study to examine the prevalence of injection drug use and associated risks among street-involved youth in Vancouver, Canada. From September 2005 to November 2007, baseline data were collected for the At-Risk Youth Study (ARYS), a prospective cohort of street-recruited youth aged 14 to 26 in Vancouver, Canada. Using multiple logistic regression, we compared youth with and without a history of injection. The sample included 560 youth among whom the median age was 21.9 years, 179 (32%) were female, and 230 (41.1%) reported prior injection drug use. Factors associated with injection drug use in multivariate analyses included age ≥ 22 years (adjusted odds ratio [AOR] = 1.18, 95% CI: 1.10–1.28); sex work involvement (AOR = 2.17, 95% CI: 1.35–3.50); non-fatal overdose (AOR = 2.10, 95% CI: 1.38–3.20); and hepatitis C (HCV) infection (AOR = 22.61, 95% CI: 7.78–65.70). These findings highlight an alarmingly high prevalence of injection drug use among street-involved youth and demonstrate its association with an array of risks and harms, including sex work involvement, overdose, and HCV infection. These findings point to the need for a broad set of policies and interventions to prevent the initiation of injection drug use and address the risks faced by street-involved youth who are actively injecting.
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影响因子：
4.4
作者：
Miller CL;Kerr T;Strathdee SA;Li K;Wood E
通讯作者：
Wood E
DOI：
10.1093/jurban/78.4.690
发表时间：
2001-12-01
影响因子：
6.6
作者：
Lifson, AR;Halcón, LL
通讯作者：
Halcón, LL
影响因子：
4.8
作者：
Molnar, BE;Shade, SB;Watters, JK
通讯作者：
Watters, JK
影响因子：
3.8
作者：
Roy, E;Haley, N;Boivin, JF
通讯作者：
Boivin, JF
影响因子：
5.2
作者：
Fairbairn, Nadia;Wood, Evan;Kerr, Thomas
通讯作者：
Kerr, Thomas