Big roles for Fat cadherins.
Big roles for Fat cadherins.
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DOI:
10.1016/j.ceb.2017.11.006
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发表时间:
2018-04
影响因子:
7.5
通讯作者:
McNeill H
中科院分区:
文献类型:
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作者:
Blair S;McNeill H
To create an intricately patterned and reproducibly sized and shaped organ, many cellular processes must be tightly regulated. Cell elongation, migration, metabolism, proliferation rates, cell-cell adhesion, planar polarization and junctional contractions all must be coordinated in time and space. Remarkably, a pair of extremely large cell adhesion molecules called Fat (Ft) and Dachsous (Ds), acting largely as a ligand-receptor system, regulate, and likely coordinate, these many diverse processes. Here we describe recent exciting progress on how the Ds-Ft pathway controls these diverse processes, and highlight a few of the many questions remaining as to how these enormous cell adhesion molecules regulate development.
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影响因子:
7.7
作者:
Bosch JA;Sumabat TM;Hafezi Y;Pellock BJ;Gandhi KD;Hariharan IK
通讯作者:
Hariharan IK
影响因子:
5.3
作者:
Alders, Marielle;Al-Gazali, Lihadh;Hennekam, Raoul C.
通讯作者:
Hennekam, Raoul C.
影响因子:
4.6
作者:
Fanto, M;Clayton, L;McNeill, H
通讯作者:
McNeill, H
影响因子:
4.6
作者:
Badouel, Caroline;Zander, Mark A.;McNeill, Helen
通讯作者:
McNeill, Helen
影响因子:
21.3
作者:
通讯作者:
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