Protein N-glycosylation and O-mannosylation are catalyzed by two evolutionarily related GT-C glycosyltransferases.
Protein N-glycosylation and O-mannosylation are catalyzed by two evolutionarily related GT-C glycosyltransferases.
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蛋白质N-糖基化和O-甘露糖基化由两种进化上相关的GT-C糖基转移酶催化。
DOI:
10.1016/j.sbi.2020.12.009
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发表时间:
2021-06
影响因子:
6.8
通讯作者:
Li H
中科院分区:
文献类型:
--
作者:
Bai L;Li H
The structural folds of glycosyltransferases are categorized into three superfamilies: GT-A, GT-B, and GT-C. Few structures of GT-C fold existed in the Protein Data Bank prior to the recent advent of high-resolution cryo-EM, because the glycosyltransferases are large membrane proteins that are difficult to crystallize. The use of cryo-EM has resulted in the structures of several key GT-C glycosyltransferases. Here we summarize the latest structural features of and mechanistic insights into these membrane enzyme complexes.
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影响因子:
64.8
作者:
Nakane T;Kotecha A;Sente A;McMullan G;Masiulis S;Brown PMGE;Grigoras IT;Malinauskaite L;Malinauskas T;Miehling J;Uchański T;Yu L;Karia D;Pechnikova EV;de Jong E;Keizer J;Bischoff M;McCormack J;Tiemeijer P;Hardwick SW;Chirgadze DY;Murshudov G;Aricescu AR;Scheres SHW
通讯作者:
Scheres SHW
影响因子:
16.6
作者:
Pfeffer S;Burbaum L;Unverdorben P;Pech M;Chen Y;Zimmermann R;Beckmann R;Förster F
通讯作者:
Förster F
影响因子:
16.6
作者:
Pfeffer S;Dudek J;Schaffer M;Ng BG;Albert S;Plitzko JM;Baumeister W;Zimmermann R;Freeze HH;Engel BD;Förster F
通讯作者:
Förster F
DOI:
10.1126/science.aar7899
发表时间:
2018-04-13
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Braunger K;Pfeffer S;Shrimal S;Gilmore R;Berninghausen O;Mandon EC;Becker T;Förster F;Beckmann R
通讯作者:
Beckmann R
影响因子:
56.9
作者:
Ramirez, Ana S.;Kowal, Julia;Locher, Kaspar P.
通讯作者:
Locher, Kaspar P.