Vinculin in cell-cell and cell-matrix adhesions.
Vinculin in cell-cell and cell-matrix adhesions.
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DOI:
10.1007/s00018-017-2511-3
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发表时间:
2017-08
期刊:
影响因子:
--
通讯作者:
DeMali KA
中科院分区:
文献类型:
--
作者:
Bays JL;DeMali KA
Vinculin was identified as a component of focal adhesions and adherens junctions nearly 40 years ago. Since that time, remarkable progress has been made in understanding its activation, regulation and function. Here we discuss the current understanding of the roles of vinculin in cell–cell and cell–matrix adhesions. Emphasis is placed on the how vinculin is recruited, activated and regulated. We also highlight the recent understanding of how vinculin responds to and transmits force at integrin- and cadherin-containing adhesion complexes to the cytoskeleton. Furthermore, we discuss roles of vinculin in binding to and rearranging the actin cytoskeleton.
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DOI:
10.1083/jcb.201309092
发表时间:
2014-04-28
期刊:
The Journal of cell biology
影响因子:
--
作者:
Bays JL;Peng X;Tolbert CE;Guilluy C;Angell AE;Pan Y;Superfine R;Burridge K;DeMali KA
通讯作者:
DeMali KA
影响因子:
6.6
作者:
Carisey, Alex;Ballestrem, Christoph
通讯作者:
Ballestrem, Christoph
影响因子:
9.2
作者:
Bachir, Alexia I.;Zareno, Jessica;Moissoglu, Konstadinos;Plow, Edward F.;Gratton, Enrico;Horwitz, Alan R.
通讯作者:
Horwitz, Alan R.
影响因子:
5.7
作者:
Borgon, RA;Vonrhein, C;Izard, T
通讯作者:
Izard, T
影响因子:
4.8
作者:
Chen, Hui;Choudhury, Dilshad M.;Craig, Susan W.
通讯作者:
Craig, Susan W.