Language networks associated with computerized semantic indices.
Language networks associated with computerized semantic indices.
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DOI：
10.1016/j.neuroimage.2014.10.008
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发表时间：
2015-01-01
期刊：
影响因子：
5.7
通讯作者：
Knopman DS
中科院分区：
文献类型：
--
作者：
Pakhomov SV;Jones DT;Knopman DS
生成语义言语流畅性测试被广泛用于研究人类大脑中概念的组织和表征。以往的研究表明，语言流畅性任务中的群集和转换行为受到与语义记忆和执行控制相关的多种脑机制的支持。以前的工作依赖于人工评估词之间的语义相关性，并将词分组为语义簇。我们研究了一种计算语言学的方法来衡量的强度的语义相关性的词的基础上的潜在语义分析的词同现在一个大型的在线百科全书的子集。我们计算了语义聚类指数，并将其与由健康参与者和受认知障碍影响的受试者组成的样本中的无任务功能磁共振成像（fMRI）获得的大脑网络连接测量结果进行了比较。我们发现，语义聚类指数与不同区域的大脑网络连接，包括额颞，额顶和梭状回区域。这项研究表明，计算机化的语义指数补充了传统的语言流畅性的评估，提供了一个更完整的帐户之间的关系，大脑和语言行为涉及组织和检索词汇信息的记忆。
Tests of generative semantic verbal fluency are widely used to study organization and representation of concepts in the human brain. Previous studies demonstrated that clustering and switching behavior during verbal fluency tasks is supported by multiple brain mechanisms associated with semantic memory and executive control. Previous work relied on manual assessments of semantic relatedness between words and grouping of words into semantic clusters. We investigated a computational linguistic approach to measuring the strength of semantic relatedness between words based on latent semantic analysis of word co-occurrences in a subset of a large online encyclopedia. We computed semantic clustering indices and compared them to brain network connectivity measures obtained with task-free fMRI in a sample consisting of healthy participants and those differentially affected by cognitive impairment. We found that semantic clustering indices were associated with brain network connectivity in distinct areas including fronto-temporal, fronto-parietal and fusiform gyrus regions. This study shows that computerized semantic indices complement traditional assessments of verbal fluency to provide a more complete account of the relationship between brain and verbal behavior involved organization and retrieval of lexical information from memory.
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影响因子：
5.7
作者：
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通讯作者：
Martin, Alex
影响因子：
5.7
作者：
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Vandenberghe, Rik
影响因子：
6
作者：
Blei, DM;Ng, AY;Jordan, MI
通讯作者：
Jordan, MI
DOI：
10.1017/s1355617706061078
发表时间：
2006-11-01
影响因子：
2.6
作者：
Baldo, Juliana V.;Schwartz, Sophie;Dronkers, Nina F.
通讯作者：
Dronkers, Nina F.
DOI：
10.1076/jcen.21.4.425.890
发表时间：
1999-08-01
影响因子：
2.2
作者：
Epker, MO;Lacritz, LH;Cullum, CM
通讯作者：
Cullum, CM