Increasing trends in hospital care burden of atrial fibrillation in Korea, 2006 through 2015
Increasing trends in hospital care burden of atrial fibrillation in Korea, 2006 through 2015
复制标题
2006 年至 2015 年韩国心房颤动医院护理负担的增加趋势
作者：
Daehoon Kim;Pil‐Sung Yang;E. Jang;H. Yu;Tae‐Hoon Kim;J. Uhm;Jong Youn Kim;H. Pak;Moon‐Hyoung Lee;B. Joung;G. Lip
目的 在迅速老龄化的亚洲国家，心房颤动 (AF) 医疗负担的时间变化不太为人所知。我们研究了韩国与 AF 相关的住院、费用、治疗模式和结果的趋势。方法 使用涉及整个韩国成年人口的国民健康保险服务 (NHIS) 数据库（2015 年 n=41 701 269），我们分析了代表 931 138 名 AF 患者的全国 AF 队列。我们研究了 2006 年至 2015 年期间所有因房颤住院的患者。结果 总体而言，从 2006 年到 2015 年，每 100 万韩国人口因房颤住院的人数从 767 人增加到 3986 人，增加了 420%。大多数入院患者年龄≥70 岁，最常见的合并症是高血压、心力衰竭和慢性阻塞性肺病。主要因大出血和房颤控制而住院的人数增加，而主要因缺血性中风和心肌梗塞住院的人数减少。即使在通货膨胀调整后，总护理费用仍从 2006 年的 6840 万欧元增加到 2015 年的 3.884 亿欧元，相当于韩国 NHIS 总支出的 0.78%。总体院内死亡率从2006年的7.5%下降到2015年的4.3%。院内死亡率最高的是≥80岁患者（7.7%）和慢性肾病患者（7.4%）。结论 过去 10 年来，韩国因房颤住院的人数呈指数级增长，这与合并慢性病的增加有关。过去十年中，与房颤住院相关的死亡率有所下降，但住院费用却显着增加。
Objective Temporal changes in the healthcare burden of atrial fibrillation (AF) are less well known in rapidly ageing Asian countries. We examined trends in hospitalisations, costs, treatment patterns and outcomes related to AF in Korea. Methods Using the National Health Insurance Service (NHIS) database involving the entire adult Korean population (n=41 701 269 in 2015), we analysed a nationwide AF cohort representing 931 138 patients with AF. We studied all hospitalisations due to AF from 2006 to 2015. Results Overall, hospitalisations for AF increased by 420% from 767 to 3986 per 1 million Korean population from 2006 to 2015. Most admissions occurred in patients aged ≥70 years, and the most frequent coexisting conditions were hypertension, heart failure and chronic obstructive pulmonary disease. Hospitalisations mainly due to major bleeding and AF control increased, whereas hospitalisations mainly due to ischaemic stroke and myocardial infarction decreased. The total cost of care increased even after adjustment for inflation from €68.4 million in 2006 to €388.4 million in 2015, equivalent to 0.78% of the Korean NHIS total expenditure. Overall in-hospital mortality decreased from 7.5% in 2006 to 4.3% in 2015. The in-hospital mortality was highest in patients ≥80 years of age (7.7%) and in patients with chronic kidney disease (7.4%). Conclusions AF hospitalisations have increased exponentially over the past 10 years in Korea, in association with an increase in comorbid chronic diseases. Mortality associated with AF hospitalisations decreased during the last decade, but hospitalisation costs have markedly increased.
影响因子：
120.7
作者：
Koton, Silvia;Schneider, Andrea L. C.;Coresh, Josef
通讯作者：
Coresh, Josef
影响因子：
39.3
作者：
Krijthe, Bouwe P.;Kunst, Anton;Heeringa, Jan
通讯作者：
Heeringa, Jan
影响因子：
120.7
作者：
Go, AS;Hylek, EM;Singer, DE
通讯作者：
Singer, DE