Population-Based Distribution and Psychometric Properties of a Short Cognitive Performance Measure in the Population-Based Heinz Nixdorf Recall Study
Population-Based Distribution and Psychometric Properties of a Short Cognitive Performance Measure in the Population-Based Heinz Nixdorf Recall Study
复制标题
基于人群的海因茨·尼克斯多夫回忆研究中短期认知表现测量的基于人群的分布和心理测量特性
作者：
N. Wege;M. Dlugaj;J. Siegrist;N. Dragano;R. Erbel;K. Jöckel;S. Moebus;C. Weimar
背景资料：鉴于这一年龄组认知功能的变异范围很广，在对早期老年人群的流行病学研究中，提供一个有效和敏感的不同领域认知表现的衡量标准是一个方法上的挑战。目的：（1）提供早期老年人群代表性样本中认知表现得分分布的数据，（2）评估在队列研究框架内开发的简短认知表现测量的心理测量特性。设计：基于人群的队列研究。设置和参与者：作为海因茨Nixdorf回忆研究的第二次检查的一部分，4,145名年龄在50-80岁之间的参与者接受了由5个子测试组成的短期认知表现评估，平均持续时间为7.31分钟。此外，656名参与者的子样本进行了详细的神经心理学和神经学检查。方法：计算总样本中特定年龄和教育程度的认知表现得分。基于子样本的数据，通过将研究结果与临床验证的神经心理学评估进行比较，检查并行有效性。结果：在总样本中，年轻和受教育程度较高的参与者的认知表现得分较高。在子样本中，观察到与临床确立的阿尔茨海默病评估量表和轻度认知障碍诊断[AUC = 0.82（0.78-0.82）]的结果相比，短期认知能力评估的准确性良好[曲线下面积（AUC）= 0.81（0.74-0.87）]。结论：这个简短的，认知性能的措施，记录良好的心理测量特性，可以是有用的，在未来的流行病学调查探索不同的领域和整体认知功能的早期老年人群。
Background: Providing a valid and sensitive measure of different domains of cognitive performance in epidemiologic studies of early old-age populations presents a methodological challenge, given the broad range of variability in cognitive functioning in this age group. Objectives: (1) To provide data on the distribution of cognitive performance scores in a representative sample of an early old-age population, and (2) to assess psychometric properties of a short cognitive performance measure developed within the framework of a cohort study. Design: Population-based cohort study. Setting and Participants: As part of the second examination of the Heinz Nixdorf Recall Study, 4,145 participants aged 50–80 years underwent a short cognitive performance assessment composed of 5 subtests with a mean duration of 7.31 min. Additionally, a subsample of 656 participants had a detailed neuropsychological and neurological examination. Methods: Age- and education-specific cognitive performance scores in the total sample were calculated. Based on data from the subsample, concurrent validity was examined by comparing findings with a clinically validated neuropsychological assessment. Results: In the total sample, younger and more highly educated participants had higher scores of cognitive performance. In the subsample, a good accuracy [area under the curve (AUC) = 0.81 (0.74–0.87)] of the short cognitive performance assessment compared with results from a clinically established Alzheimer disease assessment scale and diagnosis of mild cognitive impairment [AUC = 0.82 (0.78–0.82)] was observed. Conclusion: This brief, cognitive performance measure, documenting good psychometric properties, can be useful in future epidemiological investigations exploring different domains and overall cognitive functioning in early old-age populations.
登录
查看更多内容
影响因子：
--
作者：
Grundman, M;Petersen, RC;Thal, LJ
通讯作者：
Thal, LJ
影响因子：
--
作者：
Chen, PJ;Ratcliff, G;Ganguli, M
通讯作者：
Ganguli, M
影响因子：
2.6
作者：
Nutter-Upham, Katherine E.;Saykin, Andrew J.;Flashman, Laura A.
通讯作者：
Flashman, Laura A.
DOI：
10.1093/geronb/52b.special_issue.37
发表时间：
1997-05-01
影响因子：
6.2
作者：
Herzog, AR;Wallace, RB
通讯作者：
Wallace, RB