GoMapMan: integration, consolidation and visualization of plant gene annotations within the MapMan ontology.

GoMapMan: integration, consolidation and visualization of plant gene annotations within the MapMan ontology.
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DOI:
10.1093/nar/gkt1056
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发表时间:
2014-01
影响因子:
14.9
通讯作者:
Gruden K
Gruden K
中科院分区:
生物学2区
文献类型:
--
作者:
Ramsak Ž;Baebler Š;Rotter A;Korbar M;Mozetic I;Usadel B;Gruden K

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GoMapMan (http://www.gomapman.org)是一个开放的植物科学基因功能注释资源。它的开发是为了促进几个植物物种的基因注释的改进、整合和可视化。GoMapMan基于MapMan本体,以描述基因功能的生物概念层次树的形式组织。目前包括模式种拟南芥和3种作物(马铃薯、番茄和水稻)的基因。GoMapMan的主要特点是(1)通过各种策展选项进行动态和交互式的基因产物注释;(ii)通过整合同源类群信息整合不同植物物种的基因注释;(iii)基因本体变化和注释的可追溯性;(iv)整合来自不同公共资源的外部基因知识;(v)通过动态生成的导出文件向高通量分析工具提供收集到的信息。所有的GoMapMan功能都是公开可用的,但对管理功能有限制,管理功能需要事先注册,以确保实现的更改的可追溯性。
GoMapMan (http://www.gomapman.org) is an open web-accessible resource for gene functional annotations in the plant sciences. It was developed to facilitate improvement, consolidation and visualization of gene annotations across several plant species. GoMapMan is based on the MapMan ontology, organized in the form of a hierarchical tree of biological concepts, which describe gene functions. Currently, genes of the model species Arabidopsis and three crop species (potato, tomato and rice) are included. The main features of GoMapMan are (i) dynamic and interactive gene product annotation through various curation options; (ii) consolidation of gene annotations for different plant species through the integration of orthologue group information; (iii) traceability of gene ontology changes and annotations; (iv) integration of external knowledge about genes from different public resources; and (v) providing gathered information to high-throughput analysis tools via dynamically generated export files. All of the GoMapMan functionalities are openly available, with the restriction on the curation functions, which require prior registration to ensure traceability of the implemented changes.
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