Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer

Nodule and eminence on frenulum labii superioris: Diagnostic markers for metastatic colorectal cancer
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上唇系带上的结节和隆起:转移性结直肠癌的诊断标志物

DOI:
10.1007/s11655-014-1681-1
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发表时间:
2014-06
影响因子:
2.9
通讯作者:
Wu Xiong-zhi
Wu Xiong-zhi
中科院分区:
医学3区
文献类型:
--
作者:
Cao Rui;Wang Li-ping;Chi Jia-dong;Wu Xiong-zhi

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目的根据经络理论,探讨银角(DU28)位置上唇系带结节及隆起是否可作为大肠癌患者复发的预测依据。方法对2011年5月至2011年11月天津医科大学肿瘤医院101例结直肠癌患者资料进行分析。所有患者的上唇系带均拍照。阳性标准为上唇系带结节及隆起。对1例上唇系带大结节患者进行了活检和病理检查。结果上唇系带阳性患者的复发和转移风险高于上唇系带阴性患者。上唇系带状态与传统诊断标准在复发和/或转移诊断上无显著差异(P=0.238)。Kappa为0.606 (P<0.001)。敏感性为76.0%,特异性为85.4%。病理报告显示,上唇系带结节为黏膜赘生物,结构正常。结论上唇系带结节和隆起是转移性结直肠癌的潜在诊断标志。
ObjectiveTo determine whether the nodule and eminence on the frenulum labii superioris, location of Yinjiao (DU28) according to the meridian theory, could be used to prognosticate the recurrence of patients with colorectal cancer.MethodsThe data of 101 patients with colorectal cancer in Tianjin Medical University Cancer Institute and Hospital from May 2011 to November 2011 was analyzed. The photos of all patients’ frenulum labii superioris were taken. Nodule and eminence on frenulum labii superioris were the positive standard. Biopsy and pathological testing for the nodule were carried out on one patient with large nodule on frenulum labii superioris.ResultsPatients with positive frenulum labii superioris had a higher risk of recurrence and/or metastasis than patients with negative frenulum labii superioris. There were no significant differences in diagnosis of recurrence and/or metastasis between the status of frenulum labii superioris and the traditional diagnostic criteria (P=0.238). The Kappa was 0.606 (P<0.001). The sensitivity was 76.0% and the specificity was 85.4%. The pathological report demonstrated that the nodule on frenulum labii superioris was mucosal excrescence with normal structure.ConclusionNodule and eminence on frenulum labii superioris are potential diagnostic markers for metastatic colorectal cancer.
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