GOLPH3 keeps the Golgi residents at home.
GOLPH3 keeps the Golgi residents at home.
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DOI:
10.1083/jcb.202108147
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发表时间:
2021-10-04
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影响因子:
--
通讯作者:
Lowe M
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文献类型:
--
作者:
Lowe M
Lowe discusses recent work from Welch et al. describing a central role for GOLPH3 in sorting Golgi proteins to maintain Golgi homeostasis. In this issue of JCB, Welch et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202106115) show that GOLPH3 mediates the sorting of numerous Golgi proteins into recycling COPI transport vesicles. This explains how many resident proteins are retained at the Golgi and reveals a key role for GOLPH3 in maintaining Golgi homeostasis.
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