Dynamic properties of salmon calcitonin bound to sodium dodecyl sulfate micelles: A restrained molecular dynamics study from NMR data
Dynamic properties of salmon calcitonin bound to sodium dodecyl sulfate micelles: A restrained molecular dynamics study from NMR data
复制标题
与十二烷基硫酸钠胶束结合的鲑鱼降钙素的动态特性:根据 NMR 数据进行的受限分子动力学研究
DOI:
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发表时间:
1992
影响因子:
2.7
通讯作者:
A. Motta
中科院分区:
文献类型:
--
作者:
M. A. Castiglione Morelli;A. Pastore;A. Motta
SummaryWe have investigated the conformational behaviour of salmon calcitonin bound to sodium dodecyl sulfate micelles by means of restrained molecular dynamics simulations with both ‘static’ and time-averagen NMR distance restraints. A more realistic picture of the inherent flexibility of the hormone is obtained when using time averaging. With this apprach. long-range NOEs are interpreted better considering a dynamical exchange among different conformations.
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影响因子:
5.6
作者:
Pearlman,DA;Kollman,PA
通讯作者:
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影响因子:
2.9
作者:
Meadows,RP;Nikonowicz,EP;Jones,CR;Bastian,JW;Gorenstein,DG
通讯作者:
Gorenstein,DG
影响因子:
3.4
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