Machine learning in major depression: From classification to treatment outcome prediction.
Machine learning in major depression: From classification to treatment outcome prediction.
复制标题
重度抑郁症的机器学习:从分类到治疗结果预测。
DOI:
10.1111/cns.13048
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发表时间:
2018-11
影响因子:
5.5
通讯作者:
Sui J
中科院分区:
文献类型:
--
作者:
Gao S;Calhoun VD;Sui J
Major depression disorder (MDD) is the single greatest cause of disability and morbidity, and affects about 10% of the population worldwide. Currently, there are no clinically useful diagnostic biomarkers that are able to confirm a diagnosis of MDD from bipolar disorder (BD) in the early depressive episode. Exploring translational biomarkers of mood disorders based on machine learning is a very challenging approach, with great potential to improve our understanding of these disorders. In this paper, we review machine learning methods used for brain imaging classification and predictions, specifically, for major depression disorder, and provide an overview of studies that have used magnetic resonance imaging data to 1) classify MDDs from controls or other mood disorders; 2) investigate treatment outcome predictors for individual patients with mood disorders. Challenges, future directions and potential limitations related to MDD biomarker identification are also discussed, with a goal of offering a comprehensive overview that may help readers to better understand the applications of neuroimaging data mining in depression. We hope such efforts may highlight the need for an urgently-needed paradigm shift in treatment, to guide personalized optimal clinical care.
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影响因子:
10.6
作者:
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通讯作者:
Davatzikos C
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通讯作者:
Calhoun VD
DOI:
10.1109/titb.2008.923773
发表时间:
2009-09-01
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通讯作者:
Liu, Zhening