Patient's body composition can significantly affect RF power deposition in the tissue around DBS implants: ramifications for lead management strategies and MRI field-shaping techniques.
Patient's body composition can significantly affect RF power deposition in the tissue around DBS implants: ramifications for lead management strategies and MRI field-shaping techniques.
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患者的身体成分会显着影响DBS植入物周围组织中的射频功率沉积：对电极导线管理策略和MRI场整形技术的影响。
DOI：
10.1088/1361-6560/abcde9
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发表时间：
2021-01-14
影响因子：
3.5
通讯作者：
Golestanirad L
中科院分区：
文献类型：
--
作者：
Bhusal B;Keil B;Rosenow J;Kazemivalipour E;Golestanirad L
由于 MRI 环境中植入物的射频加热存在风险，使用深部脑刺激 (DBS) 设备等有源植入物的患者接受磁共振成像 (MRI) 的机会有限。随着人口老龄化和神经退行性疾病患病率的增加，植入此类植入物的患者进行 MRI 检查的适应症也随之增加。为了满足这种不断增长的需求，许多团体研究了减轻 MRI 期间 DBS 植入物射频加热的策略。这些努力分为两大类：MRI 场整形方法，即修改 MRI 射频线圈的电场以减少与植入导线的相互作用；以及导线管理技术，即对轨迹进行手术修改，以减少与射频场的耦合。然而，表征这些技术的研究要么依赖于同质身体模型的模拟，要么依赖于盒状单一材料模型的实验。然而，众所周知，人体的形状和异质性会影响射频电场的分布，从而改变体内植入物的加热。在这篇文章中，我们应用数值模拟和模型实验来检查患者身体成分的变化对射频功率沉积的影响程度。然后，我们评估了不同患者身体成分下射频加热缓解策略的有效性。我们的结果表明，患者的身体成分极大地改变了植入导线周围组织中的射频功率沉积。然而，这两种基于 MRI 场整形和 DBS 导联管理的技术在不同体型下都表现良好。
Patients with active implants such as deep brain stimulation (DBS) devices have limited access to magnetic resonance imaging (MRI) due to risks associated with RF heating of implants in MRI environment. With an aging population and increased prevalence of neurodegenerative disease, the indication for MRI exams in patients with such implants increases as well. In response to this growing need, many groups have investigated strategies to mitigate RF heating of DBS implants during MRI. These efforts fall into two main categories: MRI field-shaping methods, where the electric field of the MRI RF coil is modified to reduce the interaction with implanted leads, and lead management techniques where surgical modifications in the trajectory reduces the coupling with RF fields. Studies that characterize these techniques, however, have relied either on simulations with homogenous body models, or experiments with box-shaped single-material phantoms. It is well established, however, that the shape and heterogeneity of human body affects the distribution of RF electric fields, which by proxy, alters the heating of an implant inside the body. In this contribution, we applied numerical simulations and phantom experiments to examine the degree to which variations in patient’s body composition affects RF power deposition. We then assessed effectiveness of RF-heating mitigation strategies under variant patient body compositions. Our results demonstrated that patient’s body composition substantially alters RF power deposition in the tissue around implanted leads. However, both techniques based on MRI field-shaping and DBS lead management performed well under variant body types.
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影响因子：
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作者：
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