Pattern recognition analysis of anterior cingulate cortex blood flow to classify depression polarity.
Pattern recognition analysis of anterior cingulate cortex blood flow to classify depression polarity.
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DOI:
10.1192/bjp.bp.112.122838
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发表时间:
2013-09
期刊:
影响因子:
--
通讯作者:
Phillips ML
中科院分区:
文献类型:
--
作者:
Almeida JR;Mourao-Miranda J;Aizenstein HJ;Versace A;Kozel FA;Lu H;Marquand A;LaBarbara EJ;Brammer M;Trivedi M;Kupfer DJ;Phillips ML
Differentiating bipolar from recurrent unipolar depression is a major clinical challenge. In 18 healthy females and 36 females in a depressive episode - 18 with bipolar disorder type I, 18 with recurrent unipolar depression - we applied pattern recognition analysis using subdivisions of anterior cingulate cortex (ACC) blood flow at rest, measured with arterial spin labelling. Subgenual ACC blood flow classified unipolar v. bipolar depression with 81% accuracy (83% sensitivity, 78% specificity).
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