Dopamine receptor D4 allele distribution in Amerindians: a reflection of past behavior differences?
Dopamine receptor D4 allele distribution in Amerindians: a reflection of past behavior differences?
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美洲印第安人的多巴胺受体 D4 等位基因分布：反映过去的行为差异？
DOI：
10.1002/ajpa.21358
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发表时间：
2010
影响因子：
2.8
通讯作者：
M. Hutz
中科院分区：
文献类型：
--
作者：
L. Tovo;S. Callegari;M. Petzl;L. Tsuneto;F. Salzano;M. Hutz
本文报道了172名瓜拉尼人（Kaiowá和Carandeva亚群）和巴西印第安人（Kaingang）的DRD 4可变数目串联重复序列（VNTR）等位基因分布。这些结果与以前对该族裔群体获得的结果相结合。这三个群体的等位基因频率在15个其他美洲原住民群体观察到的区间内，并显示在亚马逊河流域和巴塔哥尼亚观察到的中间值。近世代狩猎采集者与农耕者的等位基因分布存在显著差异，狩猎采集者7 R等位基因的分布显著高于农耕者（P < 0.001）。分子方差分析（AMOVA）和成对F（ST）数据表明，南美洲原住民的遗传景观有三个不同的部门：安第斯山脉，中部/东南部地区和亚马逊河流域。狩猎采集者的共同特征，如寻求新奇的气质，多动和冲动，在美国史前殖民时期的新环境中可能是重要和有利的。
The DRD4 variable number of tandem repeats (VNTR) allele distribution of 172 Guarani (Kaiowá and Ñandeva subgroups) and Kaingang Brazilian Amerindians is reported. These results are integrated with those previously obtained for this ethnic group. Allele frequencies for the three populations are within the interval observed for 15 other Native American populations and show intermediate values between those observed in Amazonia and Patagonia. Significant differences in allele distribution between recent past hunter-gatherer and agriculturalist populations are observed, with an increase of the 7R allele among hunter-gatherers (P < 0.001). Analysis of molecular variance (AMOVA) and pairwise F(ST) data suggest three distinct sectors for the genetic landscape of Native South America: Andes, Center/Southeast region, and Amazonia. Common traits among hunter-gatherers such as novelty-seeking temperament, hyperactivity, and impulsivity could have been important and advantageous in new environments during America's prehistoric colonization.
影响因子：
9.8
作者：
Wang, E;Ding, YC;Moyzis, RK
通讯作者：
Moyzis, RK
影响因子：
3.3
作者：
L. Excoffier;P. Smouse;J. Quattro
通讯作者：
L. Excoffier;P. Smouse;J. Quattro
影响因子：
1.9
作者：
GUO, SW;THOMPSON, EA
通讯作者：
THOMPSON, EA