Response properties of MST parafoveal neurons during smooth pursuit adaptation.
Response properties of MST parafoveal neurons during smooth pursuit adaptation.
复制标题
MST 中心凹旁神经元在平滑追踪适应过程中的响应特性。
DOI:
10.1152/jn.00203.2016
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发表时间:
2016
影响因子:
2.5
通讯作者:
Mustari,MichaelJ
中科院分区:
文献类型:
--
作者:
Ono,Seiji;Mustari,MichaelJ
Visual motion neurons in the posterior parietal cortex play a critical role in the guidance of smooth pursuit eye movements. Initial pursuit (open-loop period) is driven, in part, by visual motion signals from cortical areas, such as the medial superior temporal area (MST). The purpose of this study was to determine whether adaptation of initial pursuit gain arises because of altered visual sensitivity of neurons at the cortical level. It is well known that the visual motion response in MST is suppressed after exposure to a large-field visual motion stimulus, showing visual motion adaptation. One hypothesis is that foveal motion responses in MST are associated with smooth pursuit adaptation using a small target spot. We used a step-ramp tracking task with two steps of target velocity (double-step paradigm), which induces gain-down or gain-up adaptation. We found that after gain-down adaptation 58% of our MST visual neurons showed a significant decrease in firing rate. This was the case even though visual motion input (before the pursuit onset) from target motion was constant. Therefore, repetitive visual stimulation during the gain-down paradigm could lead to adaptive changes in the visual response. However, the time course of adaptation did not show a correlation between the visual response and pursuit behavior. These results indicate that the visual response in MST may not directly contribute to the adaptive change in pursuit initiation.
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影响因子:
2.5
作者:
M. Takagi;D. Zee;R. Tamargo
通讯作者:
M. Takagi;D. Zee;R. Tamargo
DOI:
--
发表时间:
1996
期刊:
Neurosciences research
影响因子:
--
作者:
K. Fukushima;Masaki Tanaka;Yasuo Suzuki;J. Fukushima;Toshikazu Yoshida
通讯作者:
Toshikazu Yoshida
影响因子:
2.5
作者:
Ono,Seiji;Mustari,MichaelJ
通讯作者:
Mustari,MichaelJ
DOI:
10.1093/cercor/bhr188
发表时间:
2012
期刊:
Cerebral cortex (New York, N.Y. : 1991)
影响因子:
--
作者:
Ono,Seiji;Mustari,MichaelJ
通讯作者:
Mustari,MichaelJ
影响因子:
2.5
作者:
Ferrera,VincentP
通讯作者:
Ferrera,VincentP