Stress impairs consolidation of recognition memory after blocking drug memory reconsolidation
Stress impairs consolidation of recognition memory after blocking drug memory reconsolidation
复制标题
阻断药物记忆再巩固后，压力会损害识别记忆的巩固
DOI：
10.1016/j.neulet.2011.06.050
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发表时间：
2011-08
影响因子：
2.5
通讯作者：
Wang, Zhenyuan
中科院分区：
文献类型：
--
作者：
Zhao, Xiaojie;Li, Yang;Peng, Tao;Seese, Ronald R.;Wang, Zhenyuan
When a consolidated memory is retrieved, it returns to a vulnerable state. To persist it must undergo another process, called memory reconsolidation. It has been demonstrated that disrupting the reconsolidation of a drug-specific memory is a powerful method for intervention in drug addiction. More specifically, previous studies suggested that certain types of stress can successfully disrupt reconsolidation of drug memories. While it is typically used for a single purpose, stress contributes to a myriad of different memory paradigms and processes. These additional effects of stress on unrelated memory processes are often overlooked. In this study, cold water stress was used to assess its effects on drug memory. Rats were trained to acquire methamphetamine (MA) conditioned place preference (CPP) by confining rats to a MA-paired chamber for 10min. The new object recognition task (NOR) was given before and after stress-interrupting reconsolidation of MA-induced memory. Our data demonstrate that stress impairs the consolidation process of NOR memory when it is used to block drug memory reconsolidation, while stress exhibits no effect on acquiring a new memory, suggesting potential strategies of stress for therapeutic invention in drug addiction.
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影响因子：
3.4
作者：
Jin, Xin-Chun;Lu, Yu-Fei;Li, Bao-Ming
通讯作者：
Li, Bao-Ming
影响因子：
3.7
作者：
Retana-Márquez, S;Bonilla-Jaime, H;Velázquez-Moctezuma, J
通讯作者：
Velázquez-Moctezuma, J
影响因子：
5.2
作者：
O. Wolkowitz;S. Lupien;E. Bigler;R. B. Levin;J. Canick
通讯作者：
O. Wolkowitz;S. Lupien;E. Bigler;R. B. Levin;J. Canick
DOI：
10.1523/jneurosci.0750-08.2008
发表时间：
2008-05
期刊：
The Journal of Neuroscience
影响因子：
--
作者：
Xiao‐Yi Wang;Mei Zhao;Udi E. Ghitza;Yan-qin Li;Lin Lu
通讯作者：
Xiao‐Yi Wang;Mei Zhao;Udi E. Ghitza;Yan-qin Li;Lin Lu
影响因子：
2.7
作者：
ENNACEUR, A;DELACOUR, J
通讯作者：
DELACOUR, J