HIV Prevalence, Risk Factors for Infection, and Uptake of Prevention, Testing, and Treatment among Female Sex Workers in Namibia.

HIV Prevalence, Risk Factors for Infection, and Uptake of Prevention, Testing, and Treatment among Female Sex Workers in Namibia.
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DOI:
10.2991/jegh.k.200603.001
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发表时间:
2020-12
影响因子:
7.3
通讯作者:
Lowrance DW
Lowrance DW
中科院分区:
医学4区
文献类型:
--
作者:
Jonas A;Patel SV;Katuta F;Maher AD;Banda KM;Gerndt K;Pietersen I;Menezes de Prata N;Mutenda N;Nakanyala T;Kisting E;Kawana B;Nietschke AM;Prybylski D;McFarland W;Lowrance DW

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背景:在大多数情况下,女性性工作者(FSW)承担着全球人类免疫缺陷病毒(HIV)疾病的不成比例的负担。纳米比亚尚未公布代表性数据,为制定FSW行为和生物医学干预措施提供信息。目的:我们的目标是衡量艾滋病毒的流行率,确定感染的危险因素,并描述纳米比亚的FSW之间的预防,检测和治疗的吸收。研究方法:我们进行了横断面调查,使用响应者驱动的抽样(RDS)在纳米比亚的城市卡蒂玛Mulilo,Oshikango,斯瓦科普蒙德/鲸湾港,和温得和克。参与的FSW完成了行为问卷调查和快速艾滋病毒检测。结果如下:各城市的关键指标范围如下:艾滋病毒感染率(31.0-52.3%),在过去12个月内通过预防方案达到(46.9-73.6%),最近一次与商业性行为时使用安全套(82.1-91.1%)和非商业性(87.0-94.2%)的伴侣,并在过去12个月内进行了艾滋病毒检测或已经知道艾滋病毒阳性血清状态(56.9-82.1%)。与艾滋病毒感染有关的因素因地点而异,包括:年龄较大,有多个商业或非商业性性伴侣,失业,目前失学,教育水平较低。在艾滋病毒阳性的FSW中,57.1%的人知道自己的艾滋病毒阳性血清状态,33.7%的人正在接受抗逆转录病毒治疗。讨论:我们的研究结果表明,极高的艾滋病毒流行率和低水平的情况下,确定和治疗的FSW在纳米比亚。我们的研究结果是纳米比亚FSW中第一个代表性的基于社区的估计,可以为扩大干预措施提供信息,以减少艾滋病毒感染和传播的风险,包括预防治疗和暴露前预防。
Background: In most settings, Female Sex Workers (FSW) bear a disproportionate burden of Human Immunodeficiency Virus (HIV) disease worldwide. Representative data to inform the development of behavioral and biomedical interventions for FSW in Namibia have not been published. Objectives: Our objectives were to measure HIV prevalence, identify risk factors for infection, and describe uptake of prevention, testing, and treatment among FSW in Namibia. Methods: We conducted cross-sectional surveys using Respondent-driven Sampling (RDS) in the Namibian cities of Katima Mulilo, Oshikango, Swakopmund/Walvis Bay, and Windhoek. Participating FSW completed behavioral questionnaires and rapid HIV testing. Results: City-specific ranges of key indicators were: HIV prevalence (31.0–52.3%), reached by prevention programs in the past 12 months (46.9–73.6%), condom use at last sex with commercial (82.1–91.1%) and non-commercial (87.0–94.2%) partners, and tested for HIV within past 12 months or already aware of HIV-positive serostatus (56.9–82.1%). Factors associated with HIV infection varied by site and included: older age, having multiple commercial or non-commercial sex partners, unemployment, being currently out of school, and lower education level. Among HIV-positive FSW, 57.1% were aware of their HIV-positive serostatus and 33.7% were on antiretroviral treatment. Discussion: Our results indicate extremely high HIV prevalence and low levels of case identification and treatment among FSW in Namibia. Our results, which are the first representative community-based estimates among FSW in Namibia, can inform the scale-up of interventions to reduce the risk for HIV acquisition and onward transmission, including treatment as prevention and pre-exposure prophylaxis.
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