Growth and development of gastrointestinal cells.
Growth and development of gastrointestinal cells.
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胃肠细胞的生长和发育。
DOI：
10.1146/annurev.ph.47.030185.001135
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发表时间：
1985
影响因子：
18.2
通讯作者：
M. Lipkin
中科院分区：
文献类型：
--
作者：
M. Lipkin
我们对胃肠道细胞生长和发育的理解的最新进展来自于传统细胞动力学和生化测量的扩展以及方法学的新发展。研究正常细胞增殖的分子基础以及细胞对正常和有害刺激的生理反应的新方法得到了发展。在这些领域的研究也不断增加我们对胃肠细胞在生理和不利条件下异常发育的各个阶段的特性的理解。因此，最近的研究结果增加了我们对气肠细胞如何对改变其生长和发育的各种刺激作出反应的认识。本文将对食管、胃、小肠和大肠正常细胞和异常细胞的增殖和分化的背景资料和最新进展进行综述。我们还描述了对这一领域重要的新的生化和分析方法，它们对胃肠道细胞分子特性测量的显著扩展的贡献，以及它们的动力学和生理学相关。
Recent advances in our understanding of the growth and development of gastrointestinal cells have come from an expansion of conventional cell kinetic and biochemical measurements and from new developments in methodology. New approaches have been developed to analyze the molecular basis of cell proliferation in normal cells and the physiological responses of the cells to normal and noxious stimuli. Studies in these areas also have continued to increase our understanding of the properties of gastrointestinal cells in various stages of abnormal development, under physiological and adverse conditions. Thus , results of recent studies have increased our knowledge of how gas trointestinal cells respond to a wide variety of stimuli that alter their growth and development. In this article we will summarize background information and recent advances on the proliferation and differentiation of normal and abnormal cells of the esophagus, stomach, and small and large intestine. We also describe newer biochemical and analytical methods important to this area, their contribution to a significant expansion of measurements of molecular properties of gastrointestinal cells , and their kinetic and physiologic corre lates.
细胞增殖和损失对阿司匹林诱导的大鼠胃损伤的影响。
DOI：
10.1152/ajpgi.1982.243.6.g463
发表时间：
1982
期刊：
The American journal of physiology
影响因子：
--
作者：
Takeuchi,K;Johnson,LR
通讯作者：
Johnson,LR
人类癌前和恶性结肠上皮细胞表达胃相关抗原。
影响因子：
3.5
作者：
Higgins,PJ;Friedman,E;Lipkin,M;Hertz,R;Attiyeh,F;Stonehill,EH
通讯作者：
Stonehill,EH