Cyclic Trinuclear Diorganotin(IV) Complexes – The First Tin Compounds Bearing Oximehydroxamate Ligands: Synthesis, Structural Characterization and High In Vitro Cytotoxicity
Cyclic Trinuclear Diorganotin(IV) Complexes – The First Tin Compounds Bearing Oximehydroxamate Ligands: Synthesis, Structural Characterization and High In Vitro Cytotoxicity
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环状三核二有机锡 (IV) 配合物 — 第一种带有肟异羟肟酸酯配体的锡化合物：合成、结构表征和高体外细胞毒性
DOI：
10.1002/ejic.200900388
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发表时间：
2009-09
影响因子：
2.3
通讯作者：
李青山
中科院分区：
文献类型：
--
作者：
李青山
The reactions between equimolar amounts of R2SnO (R = Me 1, nBu 2) and N,2-dihydroxy-5-[N-hydroxyethanimidoyl]benzamide (H2L) under solvent reflux conditions (in toluene for 1 and methanol for 2) for ca. 4 h led to the formation of the trinuclear tin complexes [R2Sn(L)]3 (R = Me 3, nBu 4) isolated as colourless crystalline solids in ca. 85 % yield, which were characterized by IR, 1H, 13C and 119Sn NMR spectroscopy, elemental analysis and (for 4) by X-ray diffraction. The trinuclear Sn core is stabilized by multiple intramolecular hydrogen bonding interactions involving the hydroxamate ligands, whereas the uncoordinated oxime functions interact through intermolecular H-bonds leading to cyclic hexameric assemblies. These complexes are stable in air, soluble in common solvents and moderately in water and represent the first examples of tin species containing ligatedoximehydroxamic acids. Complex 4 exhibits high in vitrotumour-inhibiting activity against the following human cell lines: promyelocyticfina leukemia (HL-60), hepatocellular carcinoma (Bel-7402), gastric carcinoma (BGC-823) andnasopharyngeal carcinoma (KB). (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
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影响因子：
3.9
作者：
F. Pruchnik;Małgorzata Bańbuła;Z. Ciunik;H. Chojnacki;M. Latocha;B. Skop;T. Wilczok
通讯作者：
F. Pruchnik;Małgorzata Bańbuła;Z. Ciunik;H. Chojnacki;M. Latocha;B. Skop;T. Wilczok
DOI：
10.1007/978-94-011-4938-9
发表时间：
1989-08
期刊：
--
影响因子：
--
作者：
P. G. Harrison
通讯作者：
P. G. Harrison
影响因子：
3.9
作者：
A. Chaudhary;Mithlesh Agarwal;R. Singh
通讯作者：
A. Chaudhary;Mithlesh Agarwal;R. Singh
影响因子：
2.3
作者：
F. Marchetti;C. Pettinari;A. Cingolani;Lauro Brocanelli;M. Rossi;F. Caruso
通讯作者：
F. Marchetti;C. Pettinari;A. Cingolani;Lauro Brocanelli;M. Rossi;F. Caruso
DOI：
10.1039/a808681h
发表时间：
1999
期刊：
Journal of The Chemical Society-dalton Transactions
影响因子：
--
作者：
Agnieszka Dobosz;Nikolai M. Dudarenko;I. Fritsky;T. Głowiak;Aldona A. Karaczyn;H. Kozłowski;T. Sliva;J. Świątek-Kozłowska
通讯作者：
Agnieszka Dobosz;Nikolai M. Dudarenko;I. Fritsky;T. Głowiak;Aldona A. Karaczyn;H. Kozłowski;T. Sliva;J. Świątek-Kozłowska