The prevalence of dementia and depression in the elderly community in a southern European population. The Zaragoza study.
The prevalence of dementia and depression in the elderly community in a southern European population. The Zaragoza study.
复制标题
南欧老年人群中痴呆症和抑郁症的患病率。
DOI：
10.1001/archpsyc.1995.03950180083011
复制
发表时间：
1995
影响因子：
--
通讯作者：
C. de
中科院分区：
文献类型：
--
作者：
A. Lobo;P. Saz;G. Marcos;J. Día;C. de
背景
痴呆症和抑郁症患病率的国际差异令人震惊，需要进一步调查。据我们所知，这是第一项关于 DSM-III-R 痴呆症和抑郁症患病率及其在西班牙语国家和南欧老年人的代表性分层社区样本中的关系的精神病学研究。
方法
1080名老年人完成了两阶段筛查。进行了置换抽样，累积有效率达88%。在第一阶段，非专业访谈员实施了西班牙语版本的简易精神状态检查和老年精神状态表-计算机辅助分类学自动老年检查包。在第二阶段，研究精神病学家对所有可能的病例和类似数量的随机选择的可能正常的受试者使用相同的工具和病史和病因表。
结果
据估计，5.5%的老年人被认为患有痴呆症，最常见的类型是原发性退行性痴呆、阿尔茨海默氏型（4.3%）和多发性梗塞性痴呆（0.6%）。 4.8%的老年人患有抑郁症。精神疾病，特别是抑郁症，与较低的教育水平有关。 25.4% 的痴呆病例记录到“病例水平”的抑郁症，18.2% 的重度抑郁病例记录到“器质性”紊乱的病例水平。
结论
在老年人中，阿尔茨海默病和多发性梗塞性痴呆（而不是抑郁症）的患病率随着年龄的增长而急剧增加。痴呆症和抑郁症之间的重叠可能具有疾病分类学意义。较低的教育水平可能会影响精神疾病的发病率，尤其是抑郁症。
BACKGROUND
Provocative international disparities reported in the prevalence rates of dementia and depression require further investigation. This is the first psychiatric study, to the best of our knowledge, about the prevalence of DSM-III-R dementing and depressive disorders and their relationships in a representative, stratified community sample of the elderly in both a Spanish-speaking country and southern Europe.
METHODS
A two-stage screening was completed in 1080 elderly. Sampling with replacement was done, and the cumulative response rate was 88%. In phase 1, lay interviewers administered the Spanish versions of the Mini-Mental State examination and the Geriatric Mental State Schedule-Automated Geriatric Examination for Computer Assisted Taxonomy package. In phase 2, research psychiatrists administered the same instruments and the History and Aetiology Schedule to all the probable cases and a similar number of randomly selected, probably normal subjects.
RESULTS
An estimated 5.5% of the elderly were considered to have a dementing disorder, the most prevalent types being primary degenerative dementia, Alzheimer's type (4.3%), and multi-infarct dementia (0.6%). Depressive disorders were found in 4.8% of the elderly. Psychiatric morbidity, specifically depression, was associated with lower educational levels. "Case levels" of depression were documented in 25.4% of the demented cases and case levels of "organic" disturbance were seen in 18.2% of cases of major depression.
CONCLUSIONS
Among the elderly, the prevalence of Alzheimer's disease and multi-infarct dementia, as opposed to depression, increases steeply with age. The overlap found between dementia and depression may have nosological implications. There could be an effect of lower education levels on psychiatric morbidity, particularly on depression.
DOI：
10.1001/jama.1989.03430180093036
发表时间：
1989-11-10
影响因子：
120.7
作者：
EVANS, DA;FUNKENSTEIN, H;TAYLOR, JO
通讯作者：
TAYLOR, JO