Optical detection of nanoparticle agglomeration in a living system under the influence of a magnetic field
Optical detection of nanoparticle agglomeration in a living system under the influence of a magnetic field
复制标题
磁场影响下生命系统中纳米粒子团聚的光学检测
DOI：
10.1016/j.jmmm.2014.10.043
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发表时间：
2015
影响因子：
2.7
通讯作者：
W. Fritzsche
中科院分区：
文献类型：
--
作者：
R. Müller;O. Stranik;F. Schlenk;Sebastian Werner;D. Malsch;D. Fischer;W. Fritzsche
纳米颗粒在诊断和治疗中很重要。为了发挥它们的潜力，了解体内粒子的行为至关重要。然而，体外实验通常不能模拟体内的动态条件。我们工作的目的是通过粒子跟踪在磁场存在下体内观察鸡蛋容器中的粒子传输。为此，我们通过观察动脉的心动周期来证明我们在静脉中观察的空间分辨率和时间分辨率。以暗场反射和荧光模式记录显微图像。
Nanoparticles are important in diagnosis and therapy. In order to apply their potential, an understanding of the behavior of particles in the body is crucial. However,in vitroexperiments usually do not mimic the dynamic conditions of thein vivosituation. The aim of our work was anin vivoobservation of particle transport in chicken egg vessels in the presence of a magnetic field by particle tracking. For that we demonstrate the spatial resolution of our observations in a vein and a temporal resolution by observation of the cardiac cycle in an artery. Microscopic images were recorded in dark field reflection and fluorescence mode.
影响因子：
3.4
作者：
Tan J;Thomas A;Liu Y
通讯作者：
Liu Y
DOI：
10.2217/nnm.10.104
发表时间：
2010-11
期刊：
Nanomedicine (London, England)
影响因子：
--
作者：
Nacev A;Beni C;Bruno O;Shapiro B
通讯作者：
Shapiro B