The global burden of cancer: priorities for prevention.
The global burden of cancer: priorities for prevention.
复制标题
癌症的全球负担：预防优先级。
DOI：
10.1093/carcin/bgp263
复制
发表时间：
2010-01
期刊：
影响因子：
4.7
通讯作者：
Ward EM
中科院分区：
文献类型：
--
作者：
Thun MJ;DeLancey JO;Center MM;Jemal A;Ward EM
尽管美国等资源丰富的国家的癌症死亡率有所下降，但预计未来20-40年全球癌症病例和死亡人数将增加一倍以上。癌症现在是第三大死因，2007年全球估计有1.12亿新病例和760万癌症死亡病例。到2030年，预计每年将有2600万新的癌症病例和1700万癌症死亡病例。预计的增长将主要受到人口增长和老龄化的推动，并将在低资源和中等资源国家中最大。按照目前的趋势，到2050年，发展中国家寿命的延长将使活到65岁的人数增加近两倍。在许多低资源和中等资源国家，吸烟和肥胖等可改变的危险因素根深蒂固，经济发展中国家与慢性感染有关的癌症（特别是胃癌、肝癌和子宫颈癌）的下降速度比工业化国家慢，使这种人口变化更加复杂。本文确定了几种预防措施，这些措施提供了最可行的方法，以减轻最负担不起的国家预期的全球癌症增长。其中最重要的是需要加强国际烟草控制方面的努力，并在最需要的国家增加乙型肝炎和人乳头瘤病毒疫苗的供应。
Despite decreases in the cancer death rates in high-resource countries, such as the USA, the number of cancer cases and deaths is projected to more than double worldwide over the next 20–40 years. Cancer is now the third leading cause of death, with >12 million new cases and 7.6 million cancer deaths estimated to have occurred globally in 2007. By 2030, it is projected that there will be ∼26 million new cancer cases and 17 million cancer deaths per year. The projected increase will be driven largely by growth and aging of populations and will be largest in low- and medium-resource countries. Under current trends, increased longevity in developing countries will nearly triple the number of people who survive to age 65 by 2050. This demographic shift is compounded by the entrenchment of modifiable risk factors such as smoking and obesity in many low-and medium-resource countries and by the slower decline in cancers related to chronic infections (especially stomach, liver and uterine cervix) in economically developing than in industrialized countries. This paper identifies several preventive measures that offer the most feasible approach to mitigate the anticipated global increase in cancer in countries that can least afford it. Foremost among these are the need to strengthen efforts in international tobacco control and to increase the availability of vaccines against hepatitis B and human papilloma virus in countries where they are most needed.
登录
查看更多内容
影响因子：
6.4
作者：
Ezzati, M;Henley, SJ;Thun, MJ
通讯作者：
Thun, MJ
影响因子：
6.4
作者：
Everhart, JE;Kruszon-Moran, D;McQuillan, G
通讯作者：
McQuillan, G
影响因子：
25.7
作者：
Cammà, C;Giunta, M;Craxì, A
通讯作者：
Craxì, A
DOI：
10.1093/jnci/94.16.1204
发表时间：
2002-08-21
期刊：
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子：
--
作者：
Eltom, MA;Jemal, A;Biggar, RJ
通讯作者：
Biggar, RJ
影响因子：
9.7
作者：
Babus, V;Strnad, M;Balija, M
通讯作者：
Balija, M