Interdependence between iron acquisition and biofilm formation in Pseudomonas aeruginosa.

Interdependence between iron acquisition and biofilm formation in Pseudomonas aeruginosa.
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铜绿假单胞菌中的铁采集与生物膜形成之间的相互依赖性。

DOI:
10.1007/s12275-018-8114-3
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发表时间:
2018-07
期刊:
Journal of microbiology (Seoul, Korea)
影响因子:
--
通讯作者:
Kirienko NV
Kirienko NV
中科院分区:
其他
文献类型:
--
作者:
Kang D;Kirienko NV

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Bacterial biofilms remain a persistent threat to human health-care due to their role in the development of antimicrobial resistance. To combat multi-drug resistant pathogens, it is crucial to enhance our understanding of not only the regulation of biofilm formation, but also its contribution to bacterial virulence. Iron acquisition lies at the crux of these two subjects. In this review, we discuss the role of iron acquisition in biofilm formation and how hosts impede this mechanism to defend against pathogens. We also discuss recent findings that suggest that biofilm formation can also have the reciprocal effect, influencing siderophore production and iron sequestration.
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