A targeted health risk assessment following the Deepwater Horizon oil spill: polycyclic aromatic hydrocarbon exposure in Vietnamese-American shrimp consumers.
A targeted health risk assessment following the Deepwater Horizon oil spill: polycyclic aromatic hydrocarbon exposure in Vietnamese-American shrimp consumers.
复制标题
DOI：
10.1289/ehp.1408684
复制
发表时间：
2015-02
影响因子：
10.4
通讯作者：
Wickliffe JK
中科院分区：
文献类型：
--
作者：
Wilson MJ;Frickel S;Nguyen D;Bui T;Echsner S;Simon BR;Howard JL;Miller K;Wickliffe JK
Background: The Deepwater Horizon oil spill of 2010 prompted concern about health risks among seafood consumers exposed to polycyclic aromatic hydrocarbons (PAHs) via consumption of contaminated seafood. Objective: The objective of this study was to conduct population-specific probabilistic health risk assessments based on consumption of locally harvested white shrimp (Litopenaeus setiferus) among Vietnamese Americans in southeast Louisiana. Methods: We conducted a survey of Vietnamese Americans in southeast Louisiana to evaluate shrimp consumption, preparation methods, and body weight among shrimp consumers in the disaster-impacted region. We also collected and chemically analyzed locally harvested white shrimp for 81 individual PAHs. We combined the PAH levels (with accepted reference doses) found in the shrimp with the survey data to conduct Monte Carlo simulations for probabilistic noncancer health risk assessments. We also conducted probabilistic cancer risk assessments using relative potency factors (RPFs) to estimate cancer risks from the intake of PAHs from white shrimp. Results: Monte Carlo simulations were used to generate hazard quotient distributions for noncancer health risks, reported as mean ± SD, for naphthalene (1.8 × 10–4 ± 3.3 × 10–4), fluorene (2.4 × 10–5 ± 3.3 × 10–5), anthracene (3.9 × 10–6 ± 5.4 × 10–6), pyrene (3.2 × 10–5 ± 4.3 × 10–5), and fluoranthene (1.8 × 10–4 ± 3.3 × 10–4). A cancer risk distribution, based on RPF-adjusted PAH intake, was also generated (2.4 × 10–7 ± 3.9 × 10–7). Conclusions: The risk assessment results show no acute health risks or excess cancer risk associated with consumption of shrimp containing the levels of PAHs detected in our study, even among frequent shrimp consumers. Citation: Wilson MJ, Frickel S, Nguyen D, Bui T, Echsner S, Simon BR, Howard JL, Miller K, Wickliffe JK. 2015. A targeted health risk assessment following the Deepwater Horizon Oil Spill: polycyclic aromatic hydrocarbon exposure in Vietnamese-American shrimp consumers. Environ Health Perspect 123:152–159; http://dx.doi.org/10.1289/ehp.1408684
登录
查看更多内容
影响因子：
10.4
作者：
Rotkin-Ellman M;Wong KK;Solomon GM
通讯作者：
Solomon GM
影响因子：
10.4
作者：
Brown P;Brody JG;Morello-Frosch R;Tovar J;Zota AR;Rudel RA
通讯作者：
Rudel RA
影响因子：
11.4
作者：
Xia, Kang;Hagood, Gale;Folmer, Henry
通讯作者：
Folmer, Henry
DOI：
10.1016/s1383-5742(99)00016-2
发表时间：
1999-07-15
影响因子：
1.9
作者：
Phillips, DH
通讯作者：
Phillips, DH
影响因子：
11.4
作者：
Griffiths, Stewart K.
通讯作者：
Griffiths, Stewart K.